Literature DB >> 32242501

On the dynamics of a curved microtubule-associated proteins by considering viscoelastic properties of the living biological cells.

Zahra Abdelmalek1,2, Mohammed Karbon3, Arameh Eyvazian3, Ali Forooghi4, Hamed Safarpour5, Iskander Tlili6,7.   

Abstract

Over the last few years, some novel researches in the field of medical science made a tendency to have therapy without any complications or side-effects of the disease with the aid of prognosis about the behaviors of the microtubules. Regarding this issue, the stability/instability analysis of curved microtubule-associated protein in axons with attention to different size effect parameters based on an exact continuum method is presented. The real property of the living biological cells is presented as the Kelvin-Voight viscoelastic properties. Considering length scale parameter (l/R = 0.2) in modified couple stress theory (MCST) leads to a better agreement with experimental results in comparison by other theories that in the results section is presented, in detail. Based on presented exact results, the effect of R1/R parameter on the relative frequency changes of the microtubules is hardly depended to the value of the external forced load that should be attention to this value. Another important consequence is that the influence of the microtubule curvature parameter on the relative frequency changes of the living substructure is hardly depended on the value of the time-dependent viscoelastic property, that researchers in the analysis of the microtubule should be attention to this important issue.Communicated by Ramaswamy H. Sarma.

Keywords:  Dynamic modelling; biscoelastic properties; living biological cells; protein; telative frequency

Year:  2020        PMID: 32242501     DOI: 10.1080/07391102.2020.1747549

Source DB:  PubMed          Journal:  J Biomol Struct Dyn        ISSN: 0739-1102


  1 in total

1.  Gefitinib encapsulation based on nano-liposomes for enhancing the curative effect of lung cancer.

Authors:  Yanjie Hu; Jisong Zhang; Huihui Hu; Shan Xu; Li Xu; Enguo Chen
Journal:  Cell Cycle       Date:  2020-12-10       Impact factor: 4.534

  1 in total

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