Literature DB >> 32240803

"Nanogels as drug carriers - Introduction, chemical aspects, release mechanisms and potential applications".

Saurabh Shah1, Nagarjun Rangaraj1, Kritika Laxmikeshav2, Sunitha Sampathi3.   

Abstract

Nanogels, also known as next generation drug delivery systems are in the limelight of the research owing to their advantages like high loading, tunability of size, stimuli responsiveness, sustained drug release via in situ gelling mechanisms, stability, etc. Nanogels have proven to be superior in terms of reducing the complexities involved in this delivery system overcoming the drawbacks of the conventional approaches. This review will give readers an in depth understanding about basics of nanogel, classification, synthesis, advances in nanogel technology, mechanisms involved, regulatory considerations and the opportunities for further exploration in order to achieve high therapeutic efficacy for fatal diseases.
Copyright © 2020 Elsevier B.V. All rights reserved.

Keywords:  Chemical stimuli; Drug release; Nanogel; Polymer; Stimuli sensitive; Synthesis

Mesh:

Substances:

Year:  2020        PMID: 32240803     DOI: 10.1016/j.ijpharm.2020.119268

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  7 in total

Review 1.  Micro- to Nanoscale Bio-Hybrid Hydrogels Engineered by Ionizing Radiation.

Authors:  Clelia Dispenza; Daniela Giacomazza; Mats Jonsson
Journal:  Biomolecules       Date:  2020-12-31

2.  ROS-Sensitive Nanoparticles Co-delivering Dexamethasone and CDMP-1 for the Treatment of Osteoarthritis Through Chondrogenic Differentiation Induction and Inflammation Inhibition.

Authors:  Xiaodong Wu; Pengpeng Li; Jian Cheng; Qiang Xu; Beiji Lu; Conghui Han; Weiling Huo
Journal:  Front Bioeng Biotechnol       Date:  2021-01-28

Review 3.  Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing.

Authors:  Song Zhang; Jiangtao Shen; Dali Li; Yiyun Cheng
Journal:  Theranostics       Date:  2021-01-01       Impact factor: 11.556

Review 4.  Nanoparticles-based anti-aging treatment of Alzheimer's disease.

Authors:  Jian-Jian Chu; Wen-Bo Ji; Jian-Hua Zhuang; Bao-Feng Gong; Xiao-Han Chen; Wen-Bin Cheng; Wen-Danqi Liang; Gen-Ru Li; Jie Gao; You Yin
Journal:  Drug Deliv       Date:  2022-12       Impact factor: 6.819

5.  Polyvinylpyrrolidone K-30-Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement.

Authors:  Muhammad Usman Minhas; Kifayat Ullah Khan; Muhammad Sarfraz; Syed Faisal Badshah; Abubakar Munir; Kashif Barkat; Abdul Basit; Mosab Arafat
Journal:  Biomed Res Int       Date:  2022-08-26       Impact factor: 3.246

Review 6.  Physically stimulus-responsive nanoparticles for therapy and diagnosis.

Authors:  Fatemeh Farjadian; Soheila Ghasemi; Mohsen Akbarian; Mojtaba Hoseini-Ghahfarokhi; Mohsen Moghoofei; Mohammad Doroudian
Journal:  Front Chem       Date:  2022-09-14       Impact factor: 5.545

7.  Influence of the Core Formulation on Features and Drug Delivery Ability of Carbamate-Based Nanogels.

Authors:  Filippo Pinelli; Fabio Pizzetti; Óscar Fullana Ortolà; Alessandro Marchetti; Arianna Rossetti; Alessandro Sacchetti; Filippo Rossi
Journal:  Int J Mol Sci       Date:  2020-09-10       Impact factor: 5.923

  7 in total

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