Literature DB >> 32236149

Expression of Concern: Mucuna pruriens (Velvet bean) Rescues Motor, Olfactory, Mitochondrial and Synaptic Impairment in PINK1B9 Drosophila melanogaster Genetic Model of Parkinson's Disease.

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Abstract

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Year:  2020        PMID: 32236149      PMCID: PMC7112219          DOI: 10.1371/journal.pone.0231371

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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Following the publication of this article [1], concerns were raised about the reporting of the western blot data presented in Fig 6A. The bands presented in Fig 6A appear to have been spliced from the underlying gel and arranged into Fig 6A as presented in the published article. The preparation and presentation of the bands raises concerns regarding the reliability of the data presented in the published figure. The authors have informed the journal that the uncropped blots for Fig 6A are no longer available. The authors have indicated that the original data underlying other results from this study are also not available. In light of this, the article is not in compliance with the journal’s Data Availability policy in place at the time of the article’s publication. The PLOS ONE Editors issue this Expression of Concern to notify readers of the unresolved concerns pertaining to the reliability of the data presented in Fig 6A and the unavailability of underlying data to support the results presented in the article.
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1.  Mucuna pruriens (Velvet bean) rescues motor, olfactory, mitochondrial and synaptic impairment in PINK1B9 Drosophila melanogaster genetic model of Parkinson's disease.

Authors:  Simone Poddighe; Francescaelena De Rose; Roberto Marotta; Roberta Ruffilli; Maura Fanti; Pietro Paolo Secci; Maria Cristina Mostallino; Maria Dolores Setzu; Maria Antonietta Zuncheddu; Ignazio Collu; Paolo Solla; Francesco Marrosu; Sanjay Kasture; Elio Acquas; Anna Liscia
Journal:  PLoS One       Date:  2014-10-23       Impact factor: 3.240

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