Literature DB >> 32235281

Comparing open-radical cystectomy and robot-assisted radical cystectomy: current status and analysis of the evidence.

Pramit Khetrapal1, Samantha Conroy2, John D Kelly1, James W F Catto2.   

Abstract

PURPOSE OF REVIEW: Radical cystectomy is the definitive surgical treatment for aggressive bladder cancer. The robotic platform offers a new approach to radical cystectomy, but the benefits are unclear. This review examines the latest evidence, with a particular focus on developments in the last two years. RECENT
FINDINGS: Prospective evaluations of open (ORC) and robot-assisted radical cystectomy (RARC) are emerging. The radical cystectomy in patients with bladder cancer trial reported in 2018 and demonstrated oncological noninferiority for both approaches and marginal shorter length of stays with RARC using an extracorporeal reconstruction. The trial confirmed prospective randomized comparisons are possible, and replicates observations from two earlier, smaller randomised controlled trials with longer follow-up. Although there has been significant traction to the intracorporeal approach to RARC, randomized trial evidence is awaited to show any benefit over ORC.
SUMMARY: New evidence alludes to the noninferiority of the robotic platform in radical cystectomy in comparison to open surgery. There is minimal evidence of a clinically meaningful benefit. Until this is addressed, ORC remains the gold standard for the definitive surgical management of bladder cancer.

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Year:  2020        PMID: 32235281     DOI: 10.1097/MOU.0000000000000755

Source DB:  PubMed          Journal:  Curr Opin Urol        ISSN: 0963-0643            Impact factor:   2.309


  2 in total

1.  Cutaneous Ureterostomy or Ileal Conduit Urinary Diversion: Can We Spare the Bowel Following Radical Cystectomy in Patients with Solitary Functioning Kidney?

Authors:  Sumit Saini; Brusabhanu Nayak; Prashant Singh; Prabhjot Singh; Rishi Nayyar; Rajeev Kumar; Amlesh Seth
Journal:  Indian J Surg Oncol       Date:  2022-05-02

2.  A systematic review and meta-analysis of radical cystectomy in the treatment of muscular invasive bladder cancer (MIBC).

Authors:  Juan Zhao; Li Zhou; Yan Pan; Lan Chen
Journal:  Transl Androl Urol       Date:  2021-08
  2 in total

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