Takaya Yamamoto1, Yuzuru Niibe2,3, Yasuo Matsumoto4, Yasuhiro Dekura5, Ryoong-Jin Oh6, Hideomi Yamashita7, Hisao Kakuhara8, Masahiko Aoki9, Keiichi Jingu10. 1. Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan t.yamamoto@rad.med.tohoku.ac.jp. 2. Department of Radiology, Toho University Omori Medical Center, Tokyo, Japan. 3. Department of Primary Care and Medical Education, Okayama University, Okayama, Japan. 4. Department of Radiation Oncology, Niigata Cancer Center, Niigata, Japan. 5. Department of Radiation Oncology, Keiyu-kai Sapporo Hospital, Sapporo, Japan. 6. Department of Radiation Oncology, Miyakojima IGRT Clinic, Osaka, Japan. 7. Department of Radiology, University of Tokyo, Tokyo, Japan. 8. Department of Radiology, Iwate Medical University Hospital, Morioka, Japan. 9. Department of Radiation Oncology, Hirosaki University, Hirosaki, Japan. 10. Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Abstract
BACKGROUND/AIM: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. PATIENTS AND METHODS: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. RESULTS: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). CONCLUSION: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival. Copyright
BACKGROUND/AIM: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. PATIENTS AND METHODS: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. RESULTS: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). CONCLUSION: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival. Copyright