| Literature DB >> 3223403 |
Abstract
The existing knowledge of the molecular mechanism that underlies the successful engraftment of hemopoietic progenitor cells in their specific stromal microenvironment has been discussed. It appears that membrane lectins on the surface of the stem cell with specificity for galactose with and/or mannose-bearing glycoconjugates on the surface of the stromal cell are involved. This recognition and binding of hemopoietic stem cells which is called "homing" initiates the processes of differentiation, proliferation, and maturation of hemopoietic cells.Entities:
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Year: 1988 PMID： 3223403 DOI： 10.1007/978-1-4684-5571-7_16
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622