Literature DB >> 32232052

Ulcerative Colitis: Disease Burden, Impact on Daily Life, and Reluctance to Consult Medical Professionals: Results from a Japanese Internet Survey.

Toshifumi Hibi1, Toyomi Ishibashi1, Yuka Ikenoue2, Ryoichi Yoshihara3, Akiko Nihei4, Taku Kobayashi1.   

Abstract

BACKGROUND AND AIM: The prevalence of ulcerative colitis has increased in Asian populations in recent years. This Japanese internet survey investigated the symptoms, impact, and treatment of ulcerative colitis, and communication between patients and medical professionals.
METHODS: This was a non-interventional analysis of responses from participants with ulcerative colitis who had regularly visited medical providers for their disease in the past year.
RESULTS: In 501 evaluable participants, the mean age was 39.8 years and mean disease duration was 7.6 years. Ulcerative colitis had a "significant impact" on daily life in 43.5% of participants who experienced bowel urgency and 48.6% who experienced bowel incontinence. Although the prevalence of bowel urgency and bowel incontinence was associated with higher stool frequency and rectal bleeding scores (p value for trend <0.0001), they still existed even in patients without frequent stools or rectal bleeding. Around 30% of participants hesitated to discuss symptoms such as bowel incontinence with a medical professional. Approximately three-quarters preferred to use websites for medical information. Most participants (78.0%) had used topical treatments. However, 25.7% were hesitant to use such treatments due to concerns about discomfort (48.1%) and administration difficulty (47.3%).
CONCLUSIONS: Ulcerative colitis significantly affects daily life, largely due to symptoms such as bowel urgency and bowel incontinence. Despite desiring to improve bowel incontinence, patients are embarrassed to consult physicians or nurses. Therefore, medical professionals should make an active effort to draw out patients' individual concerns, including symptoms that patients may not initially feel able to talk about openly.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Bowel incontinence; Bowel urgency; Rectal bleeding; Stool frequency; Ulcerative colitis

Year:  2020        PMID: 32232052      PMCID: PMC7098303          DOI: 10.1159/000505092

Source DB:  PubMed          Journal:  Inflamm Intest Dis        ISSN: 2296-9365


  27 in total

Review 1.  Distribution and manifestations of inflammatory bowel disease in Asians, Hispanics, and African Americans: a systematic review.

Authors:  Jason K Hou; Hashem El-Serag; Selvi Thirumurthi
Journal:  Am J Gastroenterol       Date:  2009-05-26       Impact factor: 10.864

2.  Incidence and prevalence of inflammatory bowel disease in a Northern California managed care organization, 1996-2002.

Authors:  Lisa J Herrinton; Liyan Liu; James D Lewis; Patricia M Griffin; James Allison
Journal:  Am J Gastroenterol       Date:  2008-08       Impact factor: 10.864

3.  Treatment satisfaction, preferences and perception gaps between patients and physicians in the ulcerative colitis CARES study: A real world-based study.

Authors:  Laurent Peyrin-Biroulet; Gert Van Assche; Andreas Sturm; Javier P Gisbert; Daniel R Gaya; Bern Bokemeyer; Gerassimos J Mantzaris; Alessandro Armuzzi; Shaji Sebastian; Nuria Lara; Mark Lynam; Sonia Rojas-Farreras; Tao Fan; Qian Ding; Christopher M Black; Sumesh Kachroo
Journal:  Dig Liver Dis       Date:  2016-03-02       Impact factor: 4.088

Review 4.  Ulcerative colitis.

Authors:  Ryan Ungaro; Saurabh Mehandru; Patrick B Allen; Laurent Peyrin-Biroulet; Jean-Frédéric Colombel
Journal:  Lancet       Date:  2016-12-01       Impact factor: 79.321

5.  Lack of utility of symptoms and signs at first presentation as predictors of inflammatory bowel disease in secondary care.

Authors:  Alexander C Ford; Paul Moayyedi; Premysl Bercik; David G Morgan; Carolina Bolino; Maria I Pintos-Sanchez; Walter Reinisch
Journal:  Am J Gastroenterol       Date:  2015-04-28       Impact factor: 10.864

6.  Faecal incontinence in inflammatory bowel disease: associations and effect on quality of life.

Authors:  Christine Norton; Lesley B Dibley; Paul Bassett
Journal:  J Crohns Colitis       Date:  2012-12-08       Impact factor: 9.071

7.  Self-reported Symptom Burden in Individuals with Inflammatory Bowel Disease.

Authors:  Dawn Farrell; Geraldine McCarthy; Eileen Savage
Journal:  J Crohns Colitis       Date:  2015-11-22       Impact factor: 9.071

Review 8.  Pharmacotherapy of ulcerative colitis - current status and emerging trends.

Authors:  Hilal Ahmad; Vijay L Kumar
Journal:  J Basic Clin Physiol Pharmacol       Date:  2018-11-27

Review 9.  Drug therapies for ulcerative proctitis: systematic review and meta-analysis.

Authors:  Mitchell R K L Lie; Shannon L Kanis; Bettina E Hansen; C Janneke van der Woude
Journal:  Inflamm Bowel Dis       Date:  2014-11       Impact factor: 5.325

10.  Emerging Treatment Options in Mild to Moderate Ulcerative Colitis.

Authors:  Gary R Lichtenstein; Stephen B Hanauer; William J Sandborn
Journal:  Gastroenterol Hepatol (N Y)       Date:  2015-03
View more
  4 in total

1.  Notable gaps between patients' and physicians' perspectives on communication and disease management in Japan: multifaceted ad hoc analyses of the global Ulcerative Colitis Narrative Survey for further optimal care.

Authors:  Kenji Watanabe; Sean Gardiner; Shoko Arai
Journal:  Therap Adv Gastroenterol       Date:  2022-06-14       Impact factor: 4.802

2.  Urgency and Its Association With Quality of Life and Clinical Outcomes in Patients With Ulcerative Colitis.

Authors:  Jared A Sninsky; Edward L Barnes; Xian Zhang; Millie D Long
Journal:  Am J Gastroenterol       Date:  2022-02-15       Impact factor: 12.045

3.  Symptom Improvement of ulceRative colitis after an Induction dose of UStekinumab in Japanese clinical practice (SIRIUS), measured using patient-reported outcomes: a prospective observational study.

Authors:  Katsuyoshi Matsuoka; Katsumasa Nagano; Shinya Nagasaki; Yoko Murata; Tadakazu Hisamatsu
Journal:  BMJ Open       Date:  2022-05-04       Impact factor: 3.006

4.  Upadacitinib Treatment Improves Symptoms of Bowel Urgency and Abdominal Pain, and Correlates With Quality of Life Improvements in Patients With Moderate to Severe Ulcerative Colitis.

Authors:  Subrata Ghosh; Yuri Sanchez Gonzalez; Wen Zhou; Ryan Clark; Wangang Xie; Edouard Louis; Edward V Loftus; Julian Panes; Silvio Danese
Journal:  J Crohns Colitis       Date:  2021-12-18       Impact factor: 9.071

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.