| Literature DB >> 32231233 |
Jin Hyang Kim1, Alip Ghosh2, Natarajan Ayithan2, Sara Romani2, Arshi Khanam2, Jang-June Park1, Rene Rijnbrand1, Lydia Tang2, Michael J Sofia1, Shyam Kottilil2, Chris B Moore1, Bhawna Poonia3.
Abstract
An amendment to this paper has been published and can be accessed via a link at the top of the paper.Entities:
Year: 2020 PMID: 32231233 PMCID: PMC7105478 DOI: 10.1038/s41598-020-62445-6
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.379
Demographic details of cohorts of HBslo and HBshi CHB patients and healthy subjects.
| CHB (HBslo) | CHB (HBshi) | healthy donors (HD) | |
|---|---|---|---|
Serum HBsAg levels (IU/ml) | <500 | <50,000 | N/A |
| number of subjects | 23 | 16 | 10 |
median age (years) (range) | 54 (31–80) | 35 (26–60) | 37 (63–27) |
Gender (M/F) | 20/3 | 12/4 | 6/4 |
Ethnicity (Asian/African/Caucasian) | 15/5/3 | 5/11/0 | 2/0/8 |
HBV DNA (log IU/ml) (mean ± SD) | 2.07 ± 1.04 | 4.43 ± 2.36 | N/A |
HBeAg (-ve/+ve/UA) | 20/2/1 | 12/4/0 | N/A |
anti-HBeAb (-ve/+ve/UA) | 5/14/4 | 5/6/5 | N/A |
median ALT (U/L) (range) | 31.0 (9.0–542.0) | 41.0 (14.0–536.0) | N/A |
median AST (U/L) (range) | 26.0 (15.0–430.0) | 39.5 (17.0–259.0) | N/A |
SD: standard deviation, UA: Unavailable, ALT: alanine transaminase, AST: aspartate transaminase, N/A: Not applicable.
Details of subjects in second cohort of CHB patients.
| CHB | CHB | |
|---|---|---|
| number of subjects | 23 | 8 |
median age (years) (range) | 52 (34–71) | 52 (39–72) |
Gender (M/F) | 15/8 | 4/4 |
HBeAg (-ve/+ve/UA) | 14/1/8 | 1/1/6 |
UA: Unavailable.