Literature DB >> 3222465

Relative concentration of astatine-211 and iodine-125 by human fetal thyroid and carcinoma of the thyroid in nude mice.

L M Cobb1, A Harrison, N E Dudley, T E Carr, J A Humphreys.   

Abstract

The concentrations of 211At and 125I were measured in various tissues in nude mice bearing xenografts of human thyroid tissue (fetal and malignant). The relative concentration of the two halogens was obtained at 4 and 24 h after injection. Samples were taken of the host blood, muscle and thyroid gland and the grafted tissues. The mouse thyroid concentrated 125I more efficiently than 211At but the human grafts concentrated both halogens about equally.

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Year:  1988        PMID: 3222465     DOI: 10.1016/0167-8140(88)90057-6

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  3 in total

1.  Biodistribution and dosimetry of free 211At, 125I- and 131I- in rats.

Authors:  Johan Spetz; Nils Rudqvist; Eva Forssell-Aronsson
Journal:  Cancer Biother Radiopharm       Date:  2013-06-22       Impact factor: 3.099

2.  Comparison of the Therapeutic Effects of [211At]NaAt and [131I]NaI in an NIS-Expressing Thyroid Cancer Mouse Model.

Authors:  Tadashi Watabe; Yuwei Liu; Kazuko Kaneda-Nakashima; Tatsuhiko Sato; Yoshifumi Shirakami; Kazuhiro Ooe; Atsushi Toyoshima; Eku Shimosegawa; Yang Wang; Hiromitsu Haba; Takashi Nakano; Atsushi Shinohara; Jun Hatazawa
Journal:  Int J Mol Sci       Date:  2022-08-21       Impact factor: 6.208

3.  Preclinical Evaluation of Radiation-Induced Toxicity in Targeted Alpha Therapy Using [211At] NaAt in Mice: A Revisit.

Authors:  Yuwei Liu; Tadashi Watabe; Kazuko Kaneda-Nakashima; Kazuhiro Ooe; Yoshifumi Shirakami; Atsushi Toyoshima; Eku Shimosegawa; Takashi Nakano; Atsushi Shinohara; Jun Hatazawa
Journal:  Transl Oncol       Date:  2020-03-25       Impact factor: 4.243

  3 in total

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