James B Lilleker1,2, Hector Chinoy3,4,5. 1. Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, The University of Manchester, Manchester, UK. 2. Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK. 3. Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, The University of Manchester, Manchester, UK. hector.chinoy@manchester.ac.uk. 4. National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK. hector.chinoy@manchester.ac.uk. 5. Department of Rheumatology, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK. hector.chinoy@manchester.ac.uk.