Adriano Ruy Matsuo1, Wendell Arthur Lopes2, João Carlos Locatelli3, Caroline Ferraz Simões2, Gustavo Henrique de Oliveira2, Nelson Nardo1. 1. Department of Physical Education, Center of Health Sciences, State University of Maringa-UEM, Maringa, Brazil; Multidisciplinary Centre of Obesity Studies-NEMO, State University of Maringa, Maringa, Brazil. 2. Department of Physical Education, Center of Health Sciences, State University of Maringa-UEM, Maringa, Brazil; Research Group on Systemic Arterial Hypertension, Arterial Stiffness and Vascular Aging-GPHARV, State University of Maringa-UEM, Maringa, Brazil. 3. Department of Physical Education, Center of Health Sciences, State University of Maringa-UEM, Maringa, Brazil; Research Group on Systemic Arterial Hypertension, Arterial Stiffness and Vascular Aging-GPHARV, State University of Maringa-UEM, Maringa, Brazil. Electronic address: joao17_carlos@hotmail.com.
Abstract
OBJECTIVE: The aims of this study were to assess the capacity of tri-ponderal mass index (TMI) to screen and predict insulin resistance (IR) in overweight Brazilian adolescents, comparing it with body mass index (BMI) predictive capacity; and to verify the IR predictive capacity of other assessment tools such as waist circumference (WC), and waist-to-height ratio (WHR). METHODS: A cross-sectional study was carried out with 217 overweight adolescents, from both sexes, between 12 and 18 y of age. The participants were classified as having IR according to a previous established cutoff point of ≤3.16. IR was determined by the homeostasis model assessment of insulin resistance. The other assessment tools were measured with standard protocols. RESULTS: There was no difference between TMI and BMI to explain the presence of IR. In girls, BMI presented a slightly better predictive capacity to explain IR than TMI. Moreover, WC was reported to be the most effective IR screening methods for girls. Receiver operating characteristic curves showed that TMI and BMI presented similar values of sensibility and specificity for boys. Nevertheless, BMI had a better sensibility and TMI had a better specificity for girls. Interestingly, WC demonstrated a strong sensibility for both sexes. CONCLUSIONS: TMI did not present a superior predictive accuracy for IR screening in overweight Brazilian adolescents when compared with BMI. TMI and BMI presented similar values of sensitivity and specificity for boys and WC a slightly superior IR predictive capacity for girls.
OBJECTIVE: The aims of this study were to assess the capacity of tri-ponderal mass index (TMI) to screen and predict insulin resistance (IR) in overweight Brazilian adolescents, comparing it with body mass index (BMI) predictive capacity; and to verify the IR predictive capacity of other assessment tools such as waist circumference (WC), and waist-to-height ratio (WHR). METHODS: A cross-sectional study was carried out with 217 overweight adolescents, from both sexes, between 12 and 18 y of age. The participants were classified as having IR according to a previous established cutoff point of ≤3.16. IR was determined by the homeostasis model assessment of insulin resistance. The other assessment tools were measured with standard protocols. RESULTS: There was no difference between TMI and BMI to explain the presence of IR. In girls, BMI presented a slightly better predictive capacity to explain IR than TMI. Moreover, WC was reported to be the most effective IR screening methods for girls. Receiver operating characteristic curves showed that TMI and BMI presented similar values of sensibility and specificity for boys. Nevertheless, BMI had a better sensibility and TMI had a better specificity for girls. Interestingly, WC demonstrated a strong sensibility for both sexes. CONCLUSIONS:TMI did not present a superior predictive accuracy for IR screening in overweight Brazilian adolescents when compared with BMI. TMI and BMI presented similar values of sensitivity and specificity for boys and WC a slightly superior IR predictive capacity for girls.
Authors: Brianna Empringham; William J Jennings; Raeesha Rajan; Adam J Fleming; Carol Portwine; Donna L Johnston; Shayna M Zelcer; Shahrad Rod Rassekh; Victoria Tran; Sarah Burrow; Lehana Thabane; M Constantine Samaan Journal: Adolesc Health Med Ther Date: 2021-03-09
Authors: Alissa W Zhang; John T Wiernikowski; Carol Portwine; Lehana Thabane; M Constantine Samaan Journal: Sci Rep Date: 2022-01-26 Impact factor: 4.379