Literature DB >> 32215544

Cardiometabolic diseases and active aging - polypharmacy in control.

Adriana Nancy Medeiros Dos Santos1, Dulcineia Rebecca Cappelletti Nogueira1, Beatriz Aparecida Ozello Gutierrez1, Rosa Yuka Sato Chubaci1, Caroline Ribeiro de Borja Oliveira1.   

Abstract

OBJECTIVES: To estimate the prevalence of cardiometabolic diseases and their association with polypharmacy in elderly people at the University of the Third Age (Portuguese acronym: UnATI).
METHODS: A cross-sectional, descriptive, analytical study with 121 elderly patients. The prevalence ratio, Pearson's Chi-square test and Fisher's exact test were used as measures of association.
RESULTS: At the mean age of 68.3, most elderly had at least one cardiometabolic disease (82.6%), of which hypertension was the most prevalent (71.1%), and consumed prescription drugs of continuous use (92.6%). Almost half of the elderly (48.2%) used combinations of drugs, which suggests a high cardiovascular risk. Polypharmacy due to prescription was observed in almost one-third (28.6%) of the sample, associated with the use of antihypertensives (p=0.004), antidiabetics (p=0.000) or lipid-lowering agents (p<0.000).
CONCLUSIONS: Clinical guidelines recommend changes in lifestyle, but increased pharmacotherapy prevails in practice, which increases the risk of adverse events, especially in old age.

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Year:  2020        PMID: 32215544     DOI: 10.1590/0034-7167-2018-0324

Source DB:  PubMed          Journal:  Rev Bras Enferm        ISSN: 0034-7167


  1 in total

1.  Polypharmacy in the Management of Arterial Hypertension-Friend or Foe?

Authors:  Camelia Cristina Diaconu; Matei-Alexandru Cozma; Elena-Codruța Dobrică; Gina Gheorghe; Alexandra Jichitu; Vlad Alexandru Ionescu; Alina Crenguța Nicolae; Cristina Manuela Drăgoi; Mihnea-Alexandru Găman
Journal:  Medicina (Kaunas)       Date:  2021-11-23       Impact factor: 2.430

  1 in total

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