Literature DB >> 32213503

Preventive measures to avoid vertical transmission in untreated pregnant women with HIV/AIDS.

Sara Rincón Franco1,2, Montserrat Uriel1,2, Luis Martín Rodríguez2, Ximena Carolina Romero Infante3,2.   

Abstract

The HIV/AIDS during pregnancy has high morbidity and mortality, without optimal prevention and treatment. The advanced stage cases are found in developing countries due to late detection, but, also in developed countries due to immigration; therefore, the professionals should know the management steps for these patients. The implementation of specific interventions can reduce vertical transmission incidence until 1%-8%. It is presented a case of a pregnant woman with AIDS detected during first hospitalisation, due to a ventilatory failure by opportunistic germs; at the delivery the specific interventions were implemented, being able to eliminate vertical transmission to the newborn. This article explains the four main aspects to be considered for reducing vertical transmission (detection of HIV, viral load levels-CD4 lymphocyte count, way and moment of childbirth and antiretroviral therapy) and shares experiences of the management of an advanced case, in order to help professionals to handle these cases and its complications. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  HIV/AIDS; disease and health outcomes; materno-fetal medicine; neonatal health; pregnancy

Mesh:

Substances:

Year:  2020        PMID: 32213503      PMCID: PMC7167424          DOI: 10.1136/bcr-2019-233426

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  ACOG Committee Opinion No. 751: Labor and Delivery Management of Women With Human Immunodeficiency Virus Infection.

Authors: 
Journal:  Obstet Gynecol       Date:  2018-09       Impact factor: 7.661

Review 2.  Prevention of mother-to-child transmission of HIV type 1: the role of neonatal and infant prophylaxis.

Authors:  Stacey A Hurst; Kristie E Appelgren; Athena P Kourtis
Journal:  Expert Rev Anti Infect Ther       Date:  2015-02       Impact factor: 5.091

Review 3.  Elimination of perinatal HIV infection in the USA and other high-income countries: achievements and challenges.

Authors:  Steven Nesheim; Lauren Fitz Harris; Margaret Lampe
Journal:  Curr Opin HIV AIDS       Date:  2013-09       Impact factor: 4.283

4.  Guidelines for the care of pregnant women living with HIV and interventions to reduce perinatal transmission: executive summary.

Authors:  Deborah Money; Karen Tulloch; Isabelle Boucoiran; Sheila Caddy
Journal:  J Obstet Gynaecol Can       Date:  2014-08

5.  Duration of ruptured membranes and mother-to-child HIV transmission: a prospective population-based surveillance study.

Authors:  H Peters; L Byrne; A De Ruiter; K Francis; K Harding; G P Taylor; P A Tookey; C L Townsend
Journal:  BJOG       Date:  2015-05-22       Impact factor: 6.531

6.  Viraemia before, during and after pregnancy in HIV-infected women on antiretroviral therapy in rural KwaZulu-Natal, South Africa, 2010-2015.

Authors:  Terusha Chetty; Marie-Louise Newell; Claire Thorne; Anna Coutsoudis
Journal:  Trop Med Int Health       Date:  2017-11-28       Impact factor: 3.918

7.  Preterm premature rupture of membranes in human immunodeficiency virus-infected women: a novel case series.

Authors:  Kjersti M Aagaard-Tillery; Monique G Lin; Virginia Lupo; Alan Buchbinder; Patrick S Ramsey
Journal:  Infect Dis Obstet Gynecol       Date:  2006
  7 in total

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