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Literature DB >> 3221246

Anticoagulant therapy in recurrent cerebral embolism: a retrospective study in non-valvular atrial fibrillation.

H Yamanouchi¹, H Nagura, Y Ohkawa, Y Sakurai, S Kuzuhara, K Kuramoto, H Shimada, Y Toyokura.

Abstract

For the prevention of recurrent embolic stroke, 23 elderly patients with non-valvular atrial fibrillation (NVAF) were treated with oral anticoagulants (warfarin) during a mean period of 3.8 years. Only one patient suffered recurrent embolism, and another had acute myocardial infarction. There was no cerebral haemorrhage during the treatment. In an untreated control group (from an autopsy series), recurrent embolic strokes occurred in 18 of 70 NVAF patients (26%) during a mean period of 1.3 years. Long-term anticoagulant therapy appears to be effective in the prevention of recurrent embolic stroke in elderly patients with NVAF.

Entities: Chemical Disease Species

Mesh：

Substances：
Warfarin

Year: 1988 PMID： 3221246 DOI： 10.1007/bf00314482

Source DB: PubMed Journal: J Neurol ISSN： 0340-5354 Impact factor: 4.849

30 in total

3. The impact of atrial fibrillation type on the risks of thromboembolic recurrence, mortality and major haemorrhage in patients with previous stroke: A systematic review and meta-analysis of observational studies.

Authors: Antonia Mentel; Terence J Quinn; Alan C Cameron; Kennedy R Lees; Azmil H Abdul-Rahim
Journal: Eur Stroke J Date: 2020-01-13

3 in total

Anticoagulant therapy in recurrent cerebral embolism: a retrospective study in non-valvular atrial fibrillation.

1. Chronic anticoagulant therapy in recurrent embolism of cardiac origin.

2. Prophylaxis of recurrent embolism of intracardiac origin; protracted anticoagulant therapy on an ambulatory basis.

3. The clinical spectrum of hemorrhagic infarction.

4. Cerebral embolism and mitral stenosis: survival with and without anticoagulants.

5. Non-rheumatic atrial fibrillation as a risk factor for stroke.

6. Evaluation of acute cerebral ischemia for anticoagulant therapy: computed tomography or lumbar puncture.

7. Evaluation of the risk of immediate anticoagulant treatment in patients with embolic stroke of cardiac origin.

8. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study.

9. Thromboembolism in patients with atrial fibrillation.

10. Risk of recurrent stroke in patients with atrial fibrillation and non-valvular heart disease.

1. Late recurrence of embolic stroke after discontinuation of anticoagulant therapy in nonvalvular atrial fibrillation.

Review 2. Safety of treatment with oral anticoagulants in the elderly. A systematic review.

3. The impact of atrial fibrillation type on the risks of thromboembolic recurrence, mortality and major haemorrhage in patients with previous stroke: A systematic review and meta-analysis of observational studies.