Jin-Kyu Park1, Hye Won Woo2,3, Mi Kyung Kim4,5, Jinho Shin1, Young-Hoon Lee6, Dong Hoon Shin7, Min-Ho Shin8, Bo Youl Choi2,3. 1. Division of Cardiology, Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, South Korea. 2. Department of Preventive Medicine, College of Medicine, Hanyang University, Seoul, South Korea. 3. Institute for Health and Society, Hanyang University, Seoul, South Korea. 4. Department of Preventive Medicine, Medical School Building A-Room 517-2, College of Medicine, Hanyang University, 222 Wangsimni-ro, Sungdong-Gu, Seoul, 04763, Republic of Korea. kmkkim@hanyang.ac.kr. 5. Institute for Health and Society, Hanyang University, Seoul, South Korea. kmkkim@hanyang.ac.kr. 6. Department of Preventive Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, South Korea. 7. Department of Preventive Medicine, Keimyung University School of Medicine, Daegu, South Korea. 8. Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea.
Abstract
PURPOSE: Despite a beneficial role of iodine and seaweed consumption against metabolic syndrome (MetS), which is high in postmenopausal women, few studies investigated such associations in a prospective study. This study aimed to investigate the association of dietary iodine and seaweed consumption with the incidence of MetS and its components in postmenopausal women. METHODS: A total of 2588 postmenopausal women aged ≥ 40 years were recruited between 2005 and 2011 in the Multi-Rural Communities Cohort (MRCohort). A validated semiquantitative food frequency questionnaire was used to collect dietary intake data. MetS was defined as three of five components [abdominal obesity, elevated blood pressure, glucose, triglyceride, and low-high density lipoprotein cholesterol (HDL-C)] and the incidence of MetS was checked every 2-4 years. The incidence rate ratio (IRR) was estimated using a modified Poisson regression model with a robust error estimator. RESULTS: During the mean follow-up period (3.4 ± 2.1 years), MetS occurred in 481 participants. The median cumulative average iodine intake was 108.9 µg/day (interquartile range, 60.8-190.2 µg/day). In multivariable analyses, average iodine and seaweed consumption were inversely associated with MetS (IRR = 0.61, 95% CI 0.47-0.78 in the highest quartile of iodine intake, P for trend = 0.0018; IRR = 0.52, 95% CI 0.39-0.69 in the highest quartile of seaweed consumption, P for trend = 0.0004). Among MetS components, blood glucose (> 100 mg/dL), blood pressure (≥ 130/85 mmHg), and lipid profiles (triglyceride, ≥ 150 mg/dL and HDL-C, < 50 mg/dL) were significantly inversely associated with dietary iodine and seaweed consumption, but there was no clear association for waist circumference (≥ 85 cm). CONCLUSION: Dietary iodine and seaweed consumption may be inversely associated with MetS incidence and its individual abnormalities in postmenopausal women.
PURPOSE: Despite a beneficial role of iodine and seaweed consumption against metabolic syndrome (MetS), which is high in postmenopausal women, few studies investigated such associations in a prospective study. This study aimed to investigate the association of dietary iodine and seaweed consumption with the incidence of MetS and its components in postmenopausal women. METHODS: A total of 2588 postmenopausal women aged ≥ 40 years were recruited between 2005 and 2011 in the Multi-Rural Communities Cohort (MRCohort). A validated semiquantitative food frequency questionnaire was used to collect dietary intake data. MetS was defined as three of five components [abdominal obesity, elevated blood pressure, glucose, triglyceride, and low-high density lipoprotein cholesterol (HDL-C)] and the incidence of MetS was checked every 2-4 years. The incidence rate ratio (IRR) was estimated using a modified Poisson regression model with a robust error estimator. RESULTS: During the mean follow-up period (3.4 ± 2.1 years), MetS occurred in 481 participants. The median cumulative average iodine intake was 108.9 µg/day (interquartile range, 60.8-190.2 µg/day). In multivariable analyses, average iodine and seaweed consumption were inversely associated with MetS (IRR = 0.61, 95% CI 0.47-0.78 in the highest quartile of iodine intake, P for trend = 0.0018; IRR = 0.52, 95% CI 0.39-0.69 in the highest quartile of seaweed consumption, P for trend = 0.0004). Among MetS components, blood glucose (> 100 mg/dL), blood pressure (≥ 130/85 mmHg), and lipid profiles (triglyceride, ≥ 150 mg/dL and HDL-C, < 50 mg/dL) were significantly inversely associated with dietary iodine and seaweed consumption, but there was no clear association for waist circumference (≥ 85 cm). CONCLUSION: Dietary iodine and seaweed consumption may be inversely associated with MetS incidence and its individual abnormalities in postmenopausal women.
Authors: Emma S Brown; Philip J Allsopp; Pamela J Magee; Chris I R Gill; Sonja Nitecki; Conall R Strain; Emeir M McSorley Journal: Nutr Rev Date: 2014-03 Impact factor: 7.110
Authors: H V Tran; N A Erskine; C I Kiefe; B A Barton; K L Lapane; V T H Do; R J Goldberg Journal: Nutr Metab Cardiovasc Dis Date: 2017-06-15 Impact factor: 4.222
Authors: Jing Chen; Dongfeng Gu; Jianfeng Huang; Dabeeru C Rao; Cashell E Jaquish; James E Hixson; Chung-Shiuan Chen; Jichun Chen; Fanghong Lu; Dongsheng Hu; Treva Rice; Tanika N Kelly; L Lee Hamm; Paul K Whelton; Jiang He Journal: Lancet Date: 2009-02-14 Impact factor: 79.321