| Literature DB >> 32211655 |
Guo-Dong Chen1, Dan Hu, Mei-Juan Huang, Jia Tang, Xiao-Xia Wang, Jian Zou, Jun Xie, Wei-Guang Zhang, Liang-Dong Guo, Xin-Sheng Yao, Ikuro Abe, Hao Gao.
Abstract
Sporormielones A-E (1-5), novel C-C coupled orsellinic acid derivative dimers containing tricyclic cores with a dimethylcyclopentenone unit, were obtained, of which 1-3 and 5 showed obvious short-term memory improvement activity in AD flies. Based on transcriptome analysis, 13C labelling, and gene deletion, their plausible biosynthetic mechanism was proposed.Entities:
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Year: 2020 PMID： 32211655 DOI： 10.1039/d0cc00855a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222