Literature DB >> 32208659

Drug Distribution in Living Cells via Label-Free Molecular Fingerprint.

Samir F El-Mashtoly1.   

Abstract

A new application of stimulated Raman scattering (SRS) uses the benefit of a label-free molecular fingerprint to image the uptake and distribution of an alkyne-based drug in living cells. This method delivers information on cellular molecular composition and drug-cell interaction, showing the potential of SRS in drug development.

Entities:  

Year:  2020        PMID： 32208659     DOI： 10.1021/acs.jmedchem.0c00392

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  1 in total

1.  Raman and fluorescence micro-spectroscopy applied for the monitoring of sunitinib-loaded porous silicon nanocontainers in cardiac cells.

Authors:  E Tolstik; M B Gongalsky; J Dierks; T Brand; M Pernecker; N V Pervushin; D E Maksutova; K A Gonchar; J V Samsonova; G Kopeina; V Sivakov; L A Osminkina; K Lorenz
Journal:  Front Pharmacol       Date:  2022-08-09       Impact factor: 5.988
  1 in total

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