Literature DB >> 3220837

A physicochemical study of the interaction of phosphatidylinositol with buprenorphine and naloxone.

F Reig1, C Espígol, J M García Antón, G Valencia, M A Alsina.   

Abstract

The interactions of two opioid molecules (buprenorphine and naloxone) with phosphatidylinositol and phosphatidylcholine were studied in lipid monolayers at the air-water interface. The influence of Na+, Ca2+, and Mn2+ ions in these interactions has also been determined. Neither buprenorphine nor naloxone influence the ordered state of phosphatidylcholine monolayers. On the contrary, both opioid molecules interact specifically with phosphatidylinositol monolayers. The area/molecule of phosphatidylinositol spread on buprenorphine containing subphases is highly affected by this molecule and also by ions. The phosphatidylinositol/naloxone interactions are rather weak and less affected by ions.

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Year:  1988        PMID： 3220837     DOI： 10.1007/bf00762208

Source DB:  PubMed          Journal:  J Bioenerg Biomembr        ISSN： 0145-479X            Impact factor:   2.945


  22 in total

1.  [3H]U-69593 a highly selective ligand for the opioid kappa receptor.

Authors:  R A Lahti; M M Mickelson; J M McCall; P F Von Voigtlander
Journal:  Eur J Pharmacol       Date:  1985-02-26       Impact factor: 4.432

2.  Phospholipid changes in synaptic membranes by lipolytic enzymes and subsequent restoration of opiate binding with phosphatidylserine.

Authors:  L G Abood; N Salem; M MacNeil; M Butler
Journal:  Biochim Biophys Acta       Date:  1978-07-25

3.  Surface properties of acidic phospholipids: interaction of monolayers and hydrated liquid crystals with uni- and bi-valent metal ions.

Authors:  D Papahadjopoulos
Journal:  Biochim Biophys Acta       Date:  1968-09-17

4.  13C NMR chemical shift titration of metal ion-carbohydrate complexes. An unexpected dichotomy for Ca+2 binding between anomeric derivatives of N-acetylneuraminic acid.

Authors:  M F Czarniecki; E R Thornton
Journal:  Biochem Biophys Res Commun       Date:  1977-01-24       Impact factor: 3.575

5.  Design, synthesis, and binding characteristics of an opiate receptor mimetic peptide.

Authors:  W Kullmann
Journal:  J Med Chem       Date:  1984-02       Impact factor: 7.446

6.  Interactions of neomycin and calcium in synaptosomal membranes and polyphosphoinostide monolayers.

Authors:  S Lodhi; N D Weiner; J Schacht
Journal:  Biochim Biophys Acta       Date:  1976-04-05

7.  Interaction of differently oriented lipids in monolayer: mixed monolayers of 16-(9-anthroyloxy)palmitic acid with phosphatidylcholine and cholesterol.

Authors:  M Nakagaki; K Tomita; T Handa
Journal:  Biochemistry       Date:  1985-08-13       Impact factor: 3.162

8.  Binding of Ca2+ to phosphoinositols, phosphatidylserines and gangliosides.

Authors:  K Hayashi; M Mühleisen; W Probst; H Rahmann
Journal:  Chem Phys Lipids       Date:  1984-04       Impact factor: 3.329

9.  The hydrolysis of phosphatidylinositol monolayers at an air/water interface by the calcium-ion-dependent phosphatidylinositol phosphodiesterase of pig brain.

Authors:  K Hirasawa; R F Irvine; R M Dawson
Journal:  Biochem J       Date:  1981-02-01       Impact factor: 3.857

10.  Calcium binding to liposomes composed of negatively charged lipid moieties.

Authors:  M Mühleisen; W Probst; K Hayashi; H Rahmann
Journal:  Jpn J Exp Med       Date:  1983-04
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  1 in total

1.  Agonist-selective effects of opioid receptor ligands on cytosolic calcium concentration in rat striatal neurons.

Authors:  G Cristina Brailoiu; Elena Deliu; Robert Hooper; Nae J Dun; Ashiwel S Undieh; Martin W Adler; Khalid Benamar; Eugen Brailoiu
Journal:  Drug Alcohol Depend       Date:  2011-12-21       Impact factor: 4.492
  1 in total

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