| Literature DB >> 32207307 |
Junhui He1, Jianyu Dong2, Lebin Su1, Shaofeng Wu1, Lixin Liu1, Shuang-Feng Yin1, Yongbo Zhou1.
Abstract
A selective functionalization of C-C═C bonds toward N-C═O bonds is realized by an n-Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique oxidant. The systematic process involves oxygenation, nitrogenation, ring-opening, and recyclization, affording a broad range of quinazolinones in good to excellent yields.Entities:
Year: 2020 PMID： 32207307 DOI： 10.1021/acs.orglett.0c00271
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005