Literature DB >> 32206837

The role of melanins in melanotic fungi for pathogenesis and environmental survival.

Helene C Eisenman1,2, Edyta M Greer3, Carolyn W McGrail3.   

Abstract

Melanins provide fungi protection from environmental stressors, support their ecological roles, and can confer virulence in pathogens. While the function, structure, and synthesis of melanins in fungi are not fully understood, they have been shown to have varied roles. Recent research has revealed a wide range of functions, from radiation resistance to increasing virulence, shedding light on fungal diversity. Understanding fungal melanins can provide useful information, from harnessing the properties of these various melanins to targeting fungal infections.Key Points• Melanotic fungi are widespread in nature. • Melanin functions to protect fungi in the environment from a range of stresses. • Melanin contributes to pathogenesis and drug resistance of pathogenic fungi.

Entities:  

Keywords:  Antifungal; Astrobiology; Extremophile; Fungi; Melanin; Phagocytosis

Mesh:

Substances:

Year:  2020        PMID: 32206837     DOI: 10.1007/s00253-020-10532-z

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  10 in total

Review 1.  Oxidative stress response pathways in fungi.

Authors:  Hajar Yaakoub; Sara Mina; Alphonse Calenda; Jean-Philippe Bouchara; Nicolas Papon
Journal:  Cell Mol Life Sci       Date:  2022-06-01       Impact factor: 9.261

Review 2.  Melanin of fungi: from classification to application.

Authors:  Ruofan Liu; Xianfu Meng; Cuiyuan Mo; Xuetuan Wei; Aimin Ma
Journal:  World J Microbiol Biotechnol       Date:  2022-09-23       Impact factor: 4.253

3.  Beyond Melanin: Proteomics Reveals Virulence-Related Proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii Yeast Cells Grown in the Presence of L-Dihydroxyphenylalanine.

Authors:  Rodrigo Almeida-Paes; Marcos Abreu Almeida; Lilian Cristiane Baeza; Leticia Andrade Mendes Marmello; Monique Ramos de Oliveira Trugilho; Joshua Daniel Nosanchuk; Celia Maria de Almeida Soares; Richard Hemmi Valente; Rosely Maria Zancopé-Oliveira
Journal:  J Fungi (Basel)       Date:  2020-12-01

Review 4.  Current State and Future Directions of Genetics and Genomics of Endophytic Fungi for Bioprospecting Efforts.

Authors:  Rosa Sagita; Wim J Quax; Kristina Haslinger
Journal:  Front Bioeng Biotechnol       Date:  2021-03-15

5.  The Verticillium dahliae Spt-Ada-Gcn5 Acetyltransferase Complex Subunit Ada1 Is Essential for Conidia and Microsclerotia Production and Contributes to Virulence.

Authors:  Qi Geng; Huan Li; Dan Wang; Ruo-Cheng Sheng; He Zhu; Steven J Klosterman; Krishna V Subbarao; Jie-Yin Chen; Feng-Mao Chen; Dan-Dan Zhang
Journal:  Front Microbiol       Date:  2022-02-23       Impact factor: 5.640

Review 6.  Phaeohyphomycosis in China.

Authors:  Yun He; Hai-Lin Zheng; Huan Mei; Gui-Xia Lv; Wei-da Liu; Xiao-Fang Li
Journal:  Front Cell Infect Microbiol       Date:  2022-06-13       Impact factor: 6.073

7.  Dark Septate Endophytes Isolated From Wild Licorice Roots Grown in the Desert Regions of Northwest China Enhance the Growth of Host Plants Under Water Deficit Stress.

Authors:  Chao He; Wenquan Wang; Junling Hou; Xianen Li
Journal:  Front Microbiol       Date:  2021-06-23       Impact factor: 5.640

8.  Genome reduction and relaxed selection is associated with the transition to symbiosis in the basidiomycete genus Podaxis.

Authors:  Benjamin H Conlon; Cene Gostinčar; Janis Fricke; Nina B Kreuzenbeck; Jan-Martin Daniel; Malte S L Schlosser; Nils Peereboom; Duur K Aanen; Z Wilhelm de Beer; Christine Beemelmanns; Nina Gunde-Cimerman; Michael Poulsen
Journal:  iScience       Date:  2021-06-01

Review 9.  Fungal Melanin and the Mammalian Immune System.

Authors:  Sichen Liu; Sirida Youngchim; Daniel Zamith-Miranda; Joshua D Nosanchuk
Journal:  J Fungi (Basel)       Date:  2021-03-31

10.  Transcription Factors Pmr1 and Pmr2 Cooperatively Regulate Melanin Biosynthesis, Conidia Development and Secondary Metabolism in Pestalotiopsis microspora.

Authors:  Mengkai Zhou; Ze Li; Yanjie Liu; Ping Zhang; Xiaoran Hao; Xudong Zhu
Journal:  J Fungi (Basel)       Date:  2021-12-31
  10 in total

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