Literature DB >> 32206749

Salvage surgery for primary lung cancer complicated with Trousseau's syndrome after chemotherapy: a case report.

Toshinari Ema1, Hiroshi Neyatani1, Yasutaka Mochizuka2, Kazuyo Yasuda3, Saki Yamamoto1, Shuhei Iizuka1, Kazuhito Funai4, Norihiko Shiiya4.   

Abstract

A 65-year-old man was admitted to our hospital due to an abnormal shadow on chest radiographs. Chest computed tomography (CT) revealed a tumor (diameter: 38 mm × 27 mm) and another small nodule in the left upper lobe of the lung, which were accompanied by lymphangitis of the left upper lobe. The patient underwent a transbronchial lung biopsy, following which he was diagnosed with lung adenocarcinoma. Contrast-enhanced CT and ultrasound imaging revealed bilateral pulmonary artery thrombosis and multiple venous thromboses. He was thus diagnosed with stage IIB lung cancer complicated by Trousseau's syndrome. Chemotherapy was initiated using platinum doublets, while infusions of unfractionated heparin and Xa inhibitor were administered for anticoagulant therapy. Following chemotherapy, the main tumor had shrunk, and his lymphangitis, pulmonary artery thrombosis, and multiple venous thromboses had resolved. We then could perform a left upper lobectomy and lymph node dissection safely. 2020 AME Case Reports. All rights reserved.

Entities:  

Keywords:  Salvage surgery; Trousseau’s syndrome; adenocarcinoma; chemotherapy; lung cancer; thrombosis

Year:  2020        PMID: 32206749      PMCID: PMC7082236          DOI: 10.21037/acr.2019.11.05

Source DB:  PubMed          Journal:  AME Case Rep        ISSN: 2523-1995


  12 in total

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Authors:  M Mandalà; A Falanga; F Roila
Journal:  Ann Oncol       Date:  2010-05       Impact factor: 32.976

Review 2.  Trousseau's syndrome: multiple definitions and multiple mechanisms.

Authors:  Ajit Varki
Journal:  Blood       Date:  2007-05-11       Impact factor: 22.113

Review 3.  Direct oral anticoagulants in patients with VTE and cancer: a systematic review and meta-analysis.

Authors:  Maria Cristina Vedovati; Federico Germini; Giancarlo Agnelli; Cecilia Becattini
Journal:  Chest       Date:  2015-02       Impact factor: 9.410

Review 4.  Cancer-associated venous thromboembolism: Burden, mechanisms, and management.

Authors:  Cihan Ay; Ingrid Pabinger; Alexander T Cohen
Journal:  Thromb Haemost       Date:  2016-11-24       Impact factor: 5.249

5.  Prognosis of cancers associated with venous thromboembolism.

Authors:  H T Sørensen; L Mellemkjaer; J H Olsen; J A Baron
Journal:  N Engl J Med       Date:  2000-12-21       Impact factor: 91.245

6.  Venous thromboembolism prophylaxis and treatment in patients with cancer: american society of clinical oncology clinical practice guideline update 2014.

Authors:  Gary H Lyman; Kari Bohlke; Alok A Khorana; Nicole M Kuderer; Agnes Y Lee; Juan Ignacio Arcelus; Edward P Balaban; Jeffrey M Clarke; Christopher R Flowers; Charles W Francis; Leigh E Gates; Ajay K Kakkar; Nigel S Key; Mark N Levine; Howard A Liebman; Margaret A Tempero; Sandra L Wong; Mark R Somerfield; Anna Falanga
Journal:  J Clin Oncol       Date:  2015-01-20       Impact factor: 44.544

Review 7.  Treatment of venous thromboembolism in patients with cancer: A network meta-analysis comparing efficacy and safety of anticoagulants.

Authors:  Florian Posch; Oliver Königsbrügge; Christoph Zielinski; Ingrid Pabinger; Cihan Ay
Journal:  Thromb Res       Date:  2015-07-17       Impact factor: 3.944

8.  Four cases of Trousseau's syndrome associated with lung adenocarcinoma.

Authors:  Motoko Tachihara; Takefumi Nikaido; Xintao Wang; Yasuko Sato; Taeko Ishii; Kazue Saito; Satoko Sekine; Yoshinori Tanino; Takashi Ishida; Mitsuru Munakata
Journal:  Intern Med       Date:  2012-04-29       Impact factor: 1.271

9.  Clinical features of patients with lung cancer accompanied by thromboembolism or disseminated intravascular coagulation.

Authors:  Nobuhiro Kanaji; Hitoshi Mizoguchi; Takuya Inoue; Akira Tadokoro; Naoki Watanabe; Tomoya Ishii; Yasunori Tojo; Masahiro Yamaguchi; Norimitsu Kadowaki
Journal:  Ther Clin Risk Manag       Date:  2018-08-01       Impact factor: 2.423

10.  Changes in Serial D-Dimer Levels Predict the Prognoses of Trousseau's Syndrome Patients.

Authors:  Shinji Ito; Koichi Kikuchi; Akihiro Ueda; Ryunosuke Nagao; Toshiki Maeda; Kenichiro Murate; Sayuri Shima; Yasuaki Mizutani; Yoshiki Niimi; Tatsuro Mutoh
Journal:  Front Neurol       Date:  2018-07-03       Impact factor: 4.003

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