| Literature DB >> 32206605 |
J Alex Nelson1, Mahmoud Alsayed2,3, Mira Milas3,4.
Abstract
Among many recognized sequelae of primary hyperparathyroidism (PHPT), cardiovascular disease remains incompletely understood as a consequence of disordered calcium and parathyroid hormone (PTH) metabolism. While population studies have identified trends that associate PHPT with hypertension, metabolic syndrome, and vascular system calcifications, the fundamental pathophysiology, natural history, and opportunity to reverse or cure the cardiovascular effects with parathyroidectomy are not well established. This chapter reviews the current knowledge of this field of interest within PHPT and summarizes key findings from dedicated investigations that have addressed the impact of parathyroid surgery on the cardiovascular system. 2020 Gland Surgery. All rights reserved.Entities:
Keywords: Primary hyperparathyroidism (PHPT); cardiovascular; hypertension; non-dipping pattern; normocalcemic; parathyroidectomy
Year: 2020 PMID: 32206605 PMCID: PMC7082270 DOI: 10.21037/gs.2019.12.12
Source DB: PubMed Journal: Gland Surg ISSN: 2227-684X