Literature DB >> 32206155

Community pharmacy-based H. pylori screening for patients with uninvestigated dyspepsia.

John Papastergiou1,2,3, Michelle Donnelly1,2,3, Terence Yuen1,2,3, Wilson Li1,2,3, Bart van den Bemt1,2,3.   

Abstract

BACKGROUND: Helicobacter pylori is identified by the World Health Organization as a major risk factor of gastritis, peptic ulcer disease and gastric carcinomas. As point-of-care screening technology becomes more widely available, pharmacists are ideally suited to use this tool to screen patients with H. pylori infection.
PURPOSE: The objective of this study was to evaluate the feasibility of implementing point-of-care screening technology for H. pylori into community pharmacy practice and to assess the number of patients who are positively identified as a result of testing.
METHODS: Three pharmacies in Toronto, Ontario, offered H. pylori screening as part of their clinical programs. Pharmacists enrolled patients with symptoms of dyspepsia and/or receiving acid suppressant therapy for >6 weeks. Decision to screen was based on the Canadian Helicobacter Study Group Consensus (CHSG). Patients were screened using the Rapid Response H. pylori test.
RESULTS: Seventy-one patients were recruited, with a mean age of 46.3 years. Patients were ethnically diverse, with a significant proportion (59.2%) identified as being born outside of North America, including Asia (26.8%), Africa (9.9%), the Middle East (7%), Europe (9.9%) and South and Central America (5.6%). Overall, the detection rate of H. pylori infection was 21%. North Americans had the lowest incidence of an undiagnosed H. pylori infection (6.9%). Europeans (28.6%), Middle Easterners (20%) and Asians (21.1%) had a moderate incidence, followed by the highest prevalence in those of African descent (71.4%).
CONCLUSION: These results highlight the readiness of community pharmacists to adopt H. pylori screening into practice and to leverage this novel technology to positively identify and treat undiagnosed H. pylori infection. Can Pharm J (Ott) 2020;153:xx-xx.
© The Author(s) 2020.

Entities:  

Year:  2020        PMID: 32206155      PMCID: PMC7079325          DOI: 10.1177/1715163520903065

Source DB:  PubMed          Journal:  Can Pharm J (Ott)        ISSN: 1715-1635


  25 in total

Review 1.  The Toronto Consensus for the Treatment of Helicobacter pylori Infection in Adults.

Authors:  Carlo A Fallone; Naoki Chiba; Sander Veldhuyzen van Zanten; Lori Fischbach; Javier P Gisbert; Richard H Hunt; Nicola L Jones; Craig Render; Grigorios I Leontiadis; Paul Moayyedi; John K Marshall
Journal:  Gastroenterology       Date:  2016-04-19       Impact factor: 22.682

2.  Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline.

Authors:  Barbara Farrell; Kevin Pottie; Wade Thompson; Taline Boghossian; Lisa Pizzola; Farah Joy Rashid; Carlos Rojas-Fernandez; Kate Walsh; Vivian Welch; Paul Moayyedi
Journal:  Can Fam Physician       Date:  2017-05       Impact factor: 3.275

3.  ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.

Authors:  William D Chey; Grigorios I Leontiadis; Colin W Howden; Steven F Moss
Journal:  Am J Gastroenterol       Date:  2017-01-10       Impact factor: 10.864

4.  In New Survey Of Eleven Countries, US Adults Still Struggle With Access To And Affordability Of Health Care.

Authors:  Robin Osborn; David Squires; Michelle M Doty; Dana O Sarnak; Eric C Schneider
Journal:  Health Aff (Millwood)       Date:  2016-11-16       Impact factor: 6.301

Review 5.  Diagnosis of Helicobacter pylori: what should be the gold standard?

Authors:  Saurabh Kumar Patel; Chandra Bhan Pratap; Ashok Kumar Jain; Anil Kumar Gulati; Gopal Nath
Journal:  World J Gastroenterol       Date:  2014-09-28       Impact factor: 5.742

6.  Diagnosis and Treatment of Peptic Ulcer Disease and H. pylori Infection.

Authors:  Julia Fashner; Alfred C Gitu
Journal:  Am Fam Physician       Date:  2015-02-15       Impact factor: 3.292

7.  Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency.

Authors:  Jameson R Lam; Jennifer L Schneider; Wei Zhao; Douglas A Corley
Journal:  JAMA       Date:  2013-12-11       Impact factor: 56.272

Review 8.  Clinical practice: diagnosis and evaluation of dyspepsia.

Authors:  David Yates Graham; Massimo Rugge
Journal:  J Clin Gastroenterol       Date:  2010-03       Impact factor: 3.062

Review 9.  Epidemiology of Helicobacter pylori infection.

Authors:  Leonardo H Eusebi; Rocco M Zagari; Franco Bazzoli
Journal:  Helicobacter       Date:  2014-09       Impact factor: 5.753

Review 10.  Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis.

Authors:  Anca Trifan; Carol Stanciu; Irina Girleanu; Oana Cristina Stoica; Ana Maria Singeap; Roxana Maxim; Stefan Andrei Chiriac; Alin Ciobica; Lucian Boiculese
Journal:  World J Gastroenterol       Date:  2017-09-21       Impact factor: 5.742

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