Literature DB >> 32205976

Oncological Outcomes After Radical Esophagectomy from a Tertiary Cancer Center.

M P Viswanathan1, D Suresh Kumar1, G Arul Kumar1, J Sakthi Usha Devi1, D Pradeep1.   

Abstract

Although esophageal cancers have poor survival outcomes, evidence suggests that preoperative chemoradiation followed by surgery have improved survival outcomes. Minimally invasive surgery has equivalent oncological outcomes with less complication compared with open surgery, but there is insufficient data available in South Indian population. Our aim was to analyze the perioperative outcome and survival between minimally invasive and open transhiatal esophagectomy group. Data from patients operated for esophageal cancer in our department from the year 2015 to 2018 were collected retrospectively using medical records. Among 55 carcinoma esophagus patients, squamous histology (67%) and lower third location (57%) being predominant. Twenty-six patients underwent video-assisted thoracoscopic surgery (VATS)-assisted esophagectomy and 18 patients underwent open transhiatal esophagectomy. Eleven patients were inoperable. Sixteen patients in VATS arm and three patients in transhiatal arm received preoperative chemoradiation. VATS arm has lesser intraoperative blood loss, early pulmonary recovery with early intercostal drain removal, and lesser hospital stay but longer mean operating time of 171 min versus 140 min (P < 0.01). It has higher mean nodal harvest of 15 versus 7 nodes (P 0.01) and higher overall median survival of 36 months (95% CI, 29.3 to 42.7) as against 23 months (95% CI, 17.8 to 29.2) for transhiatal arm (P < 0.01). VATS-assisted esophagectomy is less morbid procedure with early postoperative recovery, better oncological outcomes, and improved survival compared with transhiatal arm which is equivalent to apex centers in India. © Indian Association of Surgical Oncology 2019.

Entities:  

Keywords:  Esophageal cancer; Preoperative chemoradiation; Survival rates; VATS esophagectomy

Year:  2019        PMID: 32205976      PMCID: PMC7064728          DOI: 10.1007/s13193-019-00996-5

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  16 in total

Review 1.  Perioperative complications of esophagectomy: Postneoadjuvant treatment versus primary surgery - Our experience and review of literature.

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Journal:  Indian J Cancer       Date:  2017 Apr-Jun       Impact factor: 1.224

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Journal:  Ann Thorac Surg       Date:  2001-07       Impact factor: 4.330

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Journal:  Surg Endosc       Date:  2010-03-05       Impact factor: 4.584

Review 4.  Transhiatal versus Ivor-Lewis oesophagectomy: is there a difference?

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Journal:  J Natl Cancer Inst       Date:  2010-08-17       Impact factor: 13.506

6.  Global incidence of oesophageal cancer by histological subtype in 2012.

Authors:  Melina Arnold; Isabelle Soerjomataram; Jacques Ferlay; David Forman
Journal:  Gut       Date:  2014-10-15       Impact factor: 23.059

7.  Two thousand transhiatal esophagectomies: changing trends, lessons learned.

Authors:  Mark B Orringer; Becky Marshall; Andrew C Chang; Julia Lee; Allan Pickens; Christine L Lau
Journal:  Ann Surg       Date:  2007-09       Impact factor: 12.969

8.  Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age.

Authors:  Linda Morris Brown; Susan S Devesa; Wong-Ho Chow
Journal:  J Natl Cancer Inst       Date:  2008-08-11       Impact factor: 13.506

Review 9.  The role of surgery in the management of oesophageal cancer.

Authors:  Peter C Wu; Mitchell C Posner
Journal:  Lancet Oncol       Date:  2003-08       Impact factor: 41.316

10.  Incidence and survival differences in esophageal cancer among ethnic groups in the United States.

Authors:  Zheling Chen; Yinghong Ren; Xianglin L Du; Jiao Yang; Yanwei Shen; Shuting Li; Yunying Wu; Meng Lv; Danfeng Dong; Enxiao Li; Wei Li; Peijun Liu; Jin Yang; Min Yi
Journal:  Oncotarget       Date:  2017-07-18
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