Despoina Manousaki1,2, Tracie A Barnett1,3,4, Marie-Eve Mathieu1,5, Katerina Maximova6, Gabrielle Simoneau1,7, Soren Harnois-Leblanc1,8, Andrea Benedetti7,9, Jennifer J McGrath10, Mélanie Henderson11,12. 1. CHU Sainte-Justine Research Center, University of Montreal, Montreal, QC, Canada. 2. Department of Human Genetics, McGill University, Montreal, QC, Canada. 3. Department of Family Medicine, McGill University, Montreal, QC, Canada. 4. Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Laval, QC, Canada. 5. Department of Kinesiology, University of Montreal, Montreal, QC, Canada. 6. School of Public Health, University of Alberta, Edmonton, AB, Canada. 7. Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada. 8. Department of Social and Preventive Medicine, School of Public Health, University of Montreal, Montreal, QC, Canada. 9. Department of Medicine, Respiratory epidemiology and clinical research unit, McGill University Health Centre, McGill University, Montréal, QC, Canada. 10. PERFORM Centre & Department of Psychology, Concordia University, Montréal, QC, Canada. 11. CHU Sainte-Justine Research Center, University of Montreal, Montreal, QC, Canada. melanie.henderson.hsj@gmail.com. 12. Department of Pediatrics, University of Montreal, Montreal, QC, Canada. melanie.henderson.hsj@gmail.com.
Abstract
BACKGROUND/ OBJECTIVES: Physical activity is beneficial to lipid profiles; however, the association between sedentary behavior and sleep and pediatric dyslipidemia remains unclear. We aimed to investigate whether sedentary behavior or sleep predicted lipid profiles in children over a 2-year period. SUBJECTS/ METHODS: Six hundered and thirty children from the QUALITY cohort, with at least one obese parent, were assessed prospectively at ages 8-10 and 10-12 years. Measures of sedentary behavior included self-reported TV viewing and computer/video game use. Seven-day accelerometry was used to derive sedentary behavior and sleep duration. Adiposity was assessed using DEXA scans. Twenty-four-hour dietary recalls yielded estimates of carbohydrate and fat intake. Outcomes included fasting total cholesterol, triglycerides, HDL and LDL-cholesterol. Multivariable models were adjusted for adiposity and diet. RESULTS: At both Visit 1 (median age 9.6 year) and Visit 2 (median age 11.6 year), children were of normal weight (55%), overweight (22%), or obese (22%). Every additional hour of TV viewing at Visit 1 was associated with a 7.0% triglyceride increase (95% CI: 3.5, 10.6; P < 0.01) and 2.6% HDL decrease (95% CI: -4.2, -0.9; P < 0.01) at Visit 2; findings remained significant after adjusting for adiposity and diet. Every additional hour of sleep at Visit 1 predicted a 4.8% LDL decrease (95% CI: -9.0, -0.5; P = 0.03) at Visit 2, after adjusting for fat intake; this association became nonsignificant once controlling for adiposity. CONCLUSIONS: Longer screen time during childhood appears to deteriorate lipid profiles in early adolescence, even after accounting for other major lifestyle habits. There is preliminary evidence of a deleterious effect of shorter sleep duration, which should be considered in further studies.
BACKGROUND/ OBJECTIVES: Physical activity is beneficial to lipid profiles; however, the association between sedentary behavior and sleep and pediatric dyslipidemia remains unclear. We aimed to investigate whether sedentary behavior or sleep predicted lipid profiles in children over a 2-year period. SUBJECTS/ METHODS: Six hundered and thirty children from the QUALITY cohort, with at least one obese parent, were assessed prospectively at ages 8-10 and 10-12 years. Measures of sedentary behavior included self-reported TV viewing and computer/video game use. Seven-day accelerometry was used to derive sedentary behavior and sleep duration. Adiposity was assessed using DEXA scans. Twenty-four-hour dietary recalls yielded estimates of carbohydrate and fat intake. Outcomes included fasting total cholesterol, triglycerides, HDL and LDL-cholesterol. Multivariable models were adjusted for adiposity and diet. RESULTS: At both Visit 1 (median age 9.6 year) and Visit 2 (median age 11.6 year), children were of normal weight (55%), overweight (22%), or obese (22%). Every additional hour of TV viewing at Visit 1 was associated with a 7.0% triglyceride increase (95% CI: 3.5, 10.6; P < 0.01) and 2.6% HDL decrease (95% CI: -4.2, -0.9; P < 0.01) at Visit 2; findings remained significant after adjusting for adiposity and diet. Every additional hour of sleep at Visit 1 predicted a 4.8% LDL decrease (95% CI: -9.0, -0.5; P = 0.03) at Visit 2, after adjusting for fat intake; this association became nonsignificant once controlling for adiposity. CONCLUSIONS: Longer screen time during childhood appears to deteriorate lipid profiles in early adolescence, even after accounting for other major lifestyle habits. There is preliminary evidence of a deleterious effect of shorter sleep duration, which should be considered in further studies.
Authors: Hyun-Sik Kang; Bernard Gutin; Paule Barbeau; Scott Owens; Christian R Lemmon; Jerry Allison; Mark S Litaker; Ngoc-Anh Le Journal: Med Sci Sports Exerc Date: 2002-12 Impact factor: 5.411
Authors: Sarah D de Ferranti; Stephen R Daniels; Matthew Gillman; Louis Vernacchio; Jorge Plutzky; Annette L Baker Journal: Clin Chem Date: 2012-06-22 Impact factor: 8.327
Authors: Thomas N Robinson; Donna M Matheson; Helena C Kraemer; Darrell M Wilson; Eva Obarzanek; Nikko S Thompson; Sofiya Alhassan; Tirzah R Spencer; K Farish Haydel; Michelle Fujimoto; Ann Varady; Joel D Killen Journal: Arch Pediatr Adolesc Med Date: 2010-11
Authors: H C McGill; C A McMahan; A W Zieske; R E Tracy; G T Malcom; E E Herderick; J P Strong Journal: Circulation Date: 2000-07-25 Impact factor: 29.690
Authors: Kam S Woo; Ping Chook; Chung W Yu; Rita Y T Sung; Mu Qiao; Sophie S F Leung; Christopher W K Lam; Con Metreweli; David S Celermajer Journal: Circulation Date: 2004-04-05 Impact factor: 29.690
Authors: Ulf Ekelund; Søren Brage; Karsten Froberg; Maarike Harro; Sigmund A Anderssen; Luis B Sardinha; Chris Riddoch; Lars Bo Andersen Journal: PLoS Med Date: 2006-12 Impact factor: 11.069
Authors: Pier Paolo Bassareo; Stephen T O'Brien; Esme Dunne; Sophie Duignan; Eliana Martino; Francesco Martino; Colin J Mcmahon Journal: Children (Basel) Date: 2022-06-30