Literature DB >> 3220127

[Dihydro-5,6-imidazo[2,1-b]thiazoles, dihydro-2,3-imidazo[2,1-b]benzothiazoles, analogs of levamisole].

H Amarouch1, P R Loiseau, M Bonnafous, R Caujolle, M Payard, P M Loiseau, C Bories, P Gayral.   

Abstract

New compounds containing 5,6-dihydro imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro imidazo[2,1-b]thiazole and 2,3-dihydro imidazo[2,1-b]benzothiazole rings, substituted by heterocycles analogue to chromones, were synthesized and screened against three nematodes, in vitro. The results indicate moderate anthelmintic properties, compared to levamisole; nevertheless, some products exhibit a significant degree of activity.

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Year:  1988        PMID: 3220127

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN: 0430-0920


  2 in total

1.  N-(3-Oxo-1-thia-4-aza-spiro-[4.5]dec-4-yl)-6-phenyl-imidazo[2,1-b][1,3]thia-zole-3-acetamide hemihydrate.

Authors:  Mehmet Akkurt; Serife Pınar Yalçın; Nuray Ulusoy Güzeldemirci; Orhan Büyükgüngör
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-04-10

2.  Inhibitory effect of new imidazole derivatives on the proliferation and nucleic acid synthesis of leukemic cells.

Authors:  J Nafziger; J J Guillosson; Y Adam; C Hecquet; M Payard; M Loiseau
Journal:  Cytotechnology       Date:  1991-07       Impact factor: 2.058

  2 in total

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