Literature DB >> 32198109

New sesquiterpenoids bearing 11-methyl ester group of agarwood.

Wei Li1, Yi-Ling Yang2, Li Yang1, Hao Wang1, Wen-Hua Dong1, Cai-Hong Cai1, Jing-Zhe Yuan1, Bei Jiang2, Wen-Li Mei3, Hao-Fu Dai4.   

Abstract

Five new sesquiterpenoids (1-5), together with a known compound 6 was isolated from ethyl ether extract of agarwood. Their structures were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR), as well as by comparison with literature data. Compound 5 exhibited inhibitory activity against acetylcholinesterase with inhibition ratio of 48.33 ± 0.17% at the concentration of 50 μg/mL.
Copyright © 2020 Elsevier B.V. All rights reserved.

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Keywords:  Acetylcholinesterase inhibitory activity; Agarwood; Sesquiterpenoid

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Year:  2020        PMID: 32198109     DOI: 10.1016/j.fitote.2020.104557

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  1 in total

1.  Zizaane-Type Sesquiterpenoids and Their Rearranged Derivatives from Agarwood of an Aquilaria Plant.

Authors:  Jing-Zhe Yuan; Yi-Ling Yang; Wei Li; Li Yang; Hao-Fu Dai; Attila Mándi; Cai-Hong Cai; Hui-Qin Chen; Wen-Hua Dong; Tibor Kurtán; Wen-Li Mei; Hao Wang
Journal:  Molecules       Date:  2021-12-29       Impact factor: 4.411

  1 in total

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