Luigi Canullo1, Marco Annunziata2, Paolo Pesce3, Grazia Tommasato4, Livia Nastri5, Luigi Guida6. 1. Private practice, Rome, Italy. 2. Associate Professor, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Naples, Italy. 3. Research Fellow, Department of Surgical Sciences (DISC), University of Genoa, Genoa, Italy. Electronic address: paolo.pesce@unige.it. 4. Doctoral student, Unit of Oral Surgery, Department of Biomedical, Surgical, and Dental Sciences, St. Paolo and St. Carlo Hospitals, University of Milan, Milan, Italy. 5. Aggregate Professor, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Naples, Italy. 6. Full Professor, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Naples, Italy.
Abstract
STATEMENT OF PROBLEM: How the properties of the implant-abutment unit may affect the peri-implant soft-tissue seal, whose stability is considered key to safeguarding the implant from bacterial contamination and preserve peri-implant health conditions, is unclear. PURPOSE: The purpose of this systematic review and meta-analysis of animal studies was to investigate whether material and surface properties of transmucosal implant components can influence the peri-implant soft-tissue adhesion at a histological level. MATERIAL AND METHODS: An electronic and hand search was conducted until August 2019. Histological animal studies comparing soft-tissue response to abutment or transmucosal collar with different materials and/or surface characteristics were selected by 2 independent reviewers. Risk of bias in individual studies was evaluated. Histomorphometric data on the dimension of the peri-implant attachment were recorded, and a quantitative synthesis by a meta-analysis was performed. Risk of bias in individual studies was evaluated in accordance with the Systematic Review Centre for Laboratory Animal Experimentation Risk of Bias tool. RESULTS: Eighteen relevant studies out of 1187 were identified, none with a low risk of bias for all domains. Data from only 4 studies could be meta-analyzed. Comparable results in terms of peri-implant attachment dimensions between test and control groups were found, except for a significantly higher apical junctional epithelium to coronal bone to implant (ajE-CBI) distance for chemically modified acid-etched compared with titanium machined surfaces. Non-meta-analyzable and/or qualitative results highlighted some improved properties also for microgrooved and oxidized surfaces. CONCLUSIONS: Limited data from animal studies suggest that some characteristics of the transmucosal implant components may affect peri-implant soft-tissue adhesion and stabilization but do not allow definitive conclusions. Future research should improve study design to increase the availability of comparable and suitable data on this topic.
STATEMENT OF PROBLEM: How the properties of the implant-abutment unit may affect the peri-implant soft-tissue seal, whose stability is considered key to safeguarding the implant from bacterial contamination and preserve peri-implant health conditions, is unclear. PURPOSE: The purpose of this systematic review and meta-analysis of animal studies was to investigate whether material and surface properties of transmucosal implant components can influence the peri-implant soft-tissue adhesion at a histological level. MATERIAL AND METHODS: An electronic and hand search was conducted until August 2019. Histological animal studies comparing soft-tissue response to abutment or transmucosal collar with different materials and/or surface characteristics were selected by 2 independent reviewers. Risk of bias in individual studies was evaluated. Histomorphometric data on the dimension of the peri-implant attachment were recorded, and a quantitative synthesis by a meta-analysis was performed. Risk of bias in individual studies was evaluated in accordance with the Systematic Review Centre for Laboratory Animal Experimentation Risk of Bias tool. RESULTS: Eighteen relevant studies out of 1187 were identified, none with a low risk of bias for all domains. Data from only 4 studies could be meta-analyzed. Comparable results in terms of peri-implant attachment dimensions between test and control groups were found, except for a significantly higher apical junctional epithelium to coronal bone to implant (ajE-CBI) distance for chemically modified acid-etched compared with titanium machined surfaces. Non-meta-analyzable and/or qualitative results highlighted some improved properties also for microgrooved and oxidized surfaces. CONCLUSIONS: Limited data from animal studies suggest that some characteristics of the transmucosal implant components may affect peri-implant soft-tissue adhesion and stabilization but do not allow definitive conclusions. Future research should improve study design to increase the availability of comparable and suitable data on this topic.
Authors: Leandro Amadeu Roth; Marta Ferreira Bastos; Marcelo A Melo; Valentim A R Barão; Raphael C Costa; Gabriela Giro; João Gabriel Silva Souza; Kinga Grzech-Leśniak; Jamil Awad Shibli Journal: Life (Basel) Date: 2022-06-22
Authors: Vygandas Rutkunas; Rokas Borusevicius; Dominyka Liaudanskaite; Urte Jasinskyte; Saulius Drukteinis; Virginija Bukelskiene; Eitan Mijiritsky Journal: Int J Environ Res Public Health Date: 2020-10-23 Impact factor: 3.390
Authors: Francesco Gianfreda; Patrizio Bollero; Maurizio Muzzi; Andrea Di Giulio; Eleonora Nicolai; Luigi Canullo Journal: Dent J (Basel) Date: 2022-03-01