BACKGROUND: Young women with breast cancer (YWBC) are more likely to have aggressive disease, carry mutations for hereditary cancer genes, and experience higher mortality. They also may face reduced fertility because of the toxicity of chemotherapy. OBJECTIVES: This article aims to present a review of YWBC treatments, sequelae of treatment, and psychosocial challenges. METHODS: The authors performed a review of guideline-supported treatment options, patient resources, and nursing implications. FINDINGS: Because of high-risk cancers and a lack of specific treatment guidelines, healthcare providers may consider aggressive treatments for younger patients. However, studies indicate that the foundation for treatment decisions for YWBC are best based on disease stage and National Comprehensive Cancer Network guidelines.
BACKGROUND: Young women with breast cancer (YWBC) are more likely to have aggressive disease, carry mutations for hereditary cancer genes, and experience higher mortality. They also may face reduced fertility because of the toxicity of chemotherapy. OBJECTIVES: This article aims to present a review of YWBC treatments, sequelae of treatment, and psychosocial challenges. METHODS: The authors performed a review of guideline-supported treatment options, patient resources, and nursing implications. FINDINGS: Because of high-risk cancers and a lack of specific treatment guidelines, healthcare providers may consider aggressive treatments for younger patients. However, studies indicate that the foundation for treatment decisions for YWBC are best based on disease stage and National Comprehensive Cancer Network guidelines.
Entities:
Keywords:
breast cancer; fertility; genetic testing; treatment; young women
Authors: Niklas Paul Grusdat; Alexander Stäuber; Marion Tolkmitt; Jens Schnabel; Birgit Schubotz; Peter Richard Wright; Henry Schulz Journal: Support Care Cancer Date: 2022-01-11 Impact factor: 3.359