Literature DB >> 32195900

Factors Behind Decline of Venovenous Extracorporeal Membrane Oxygenation to Support Neonatal Respiratory Failure.

Jon Lillie1, Liz Boot, Simone Speggiorin, Andrew G Nyman.   

Abstract

OBJECTIVES: Neonates with respiratory failure are ideally supported with venovenous rather than venoarterial extracorporeal membrane oxygenation due to the reduced rate of neurologic complications. However, the proportion of neonates supported with venovenous extracorporeal membrane oxygenation is declining. We aimed to explore the factors behind this decline.
DESIGN: We conducted a survey in order to understand current practice across the United Kingdom, exploring barriers to neonatal venovenous extracorporeal membrane oxygenation in addition to collecting U.K.-wide retrospective data from 2000 onwards. PATIENTS: Neonates with respiratory failure supported with extracorporeal membrane oxygenation in the United Kingdom.
SETTING: All 11 pediatric U.K. extracorporeal membrane oxygenation centers provided data.
INTERVENTIONS: None.
MEASUREMENTS AND MAIN RESULTS: The percentage of neonates with respiratory failure supported with venovenous extracorporeal membrane oxygenation has declined from 58% to 16% over the last decade, reflected internationally with a decrease of 1.3% per year. Nine extracorporeal membrane oxygenation centers are able to offer pediatric venovenous extracorporeal membrane oxygenation, but only four offer neonatal venovenous extracorporeal membrane oxygenation. Of those able to provide neonatal venovenous extracorporeal membrane oxygenation, three centers use dual lumen cannulae and one uses neonatal multisite cannulation. The most frequently cited barriers to neonatal venovenous extracorporeal membrane oxygenation were the lack of availability of a suitable dual lumen cannula with concerns of cardiac perforation and challenges of multisite cannulation due to small caliber femoral veins.
CONCLUSIONS: The majority of U.K. centers are unable to provide venovenous extracorporeal membrane oxygenation for neonates due to concerns with availability and suitability of dual lumen cannulae. An alternative to be considered is the use of multisite cannulation, which has been used historically and is currently being used in centers internationally and in the United Kingdom.

Entities:  

Mesh:

Year:  2020        PMID: 32195900     DOI: 10.1097/PCC.0000000000002340

Source DB:  PubMed          Journal:  Pediatr Crit Care Med        ISSN: 1529-7535            Impact factor:   3.624


  2 in total

1.  [Application of two noninvasive scores in predicting the risk of respiratory failure in full-term neonates: a comparative analysis].

Authors:  Yan-Hong Zhao; Ya-Juan Liu; Xiao-Li Zhao; Wei-Chao Chen; Yi-Xian Zhou
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2022-04-15

2.  Hidden Harlequin syndrome in neonatal and pediatric VA-ECMO.

Authors:  Yael Levy; Julie Starck; Anne-Lise Mary; Yohan Soreze; Sandrine Jean; Bernard Kreitmann; Pierre-Louis Léger; Jerome Rambaud
Journal:  Crit Care       Date:  2022-05-20       Impact factor: 19.334

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.