Literature DB >> 32195005

Mitochondrial dysfunction and alcohol-associated liver disease: a novel pathway and therapeutic target.

Mohamed A Abdallah1,2, Ashwani K Singal2,3.   

Abstract

Keywords:  Gastroenterology; Molecular biology

Year:  2020        PMID: 32195005      PMCID: PMC7054548          DOI: 10.1038/s41392-020-0128-8

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN: 2059-3635


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  9 in total

1.  An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice.

Authors:  A Mansouri; I Gaou; C De Kerguenec; S Amsellem; D Haouzi; A Berson; A Moreau; G Feldmann; P Lettéron; D Pessayre; B Fromenty
Journal:  Gastroenterology       Date:  1999-07       Impact factor: 22.682

2.  Orphan receptor TR3 enhances p53 transactivation and represses DNA double-strand break repair in hepatoma cells under ionizing radiation.

Authors:  Bi-xing Zhao; Hang-zi Chen; Xiao-dan Du; Jie Luo; Jian-ping He; Rong-hao Wang; Yuan Wang; Rong Wu; Ru-rong Hou; Ming Hong; Qiao Wu
Journal:  Mol Endocrinol       Date:  2011-06-09

Review 3.  Recent updates on alcoholic hepatitis.

Authors:  Lindsey C Shipley; Sudha Kodali; Ashwani K Singal
Journal:  Dig Liver Dis       Date:  2019-04-19       Impact factor: 4.088

Review 4.  Antioxidants as therapeutic agents for liver disease.

Authors:  Ashwani K Singal; Sarat C Jampana; Steven A Weinman
Journal:  Liver Int       Date:  2011-07-29       Impact factor: 5.828

5.  NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α.

Authors:  Hao Zhou; Jin Wang; Pingjun Zhu; Hong Zhu; Sam Toan; Shunying Hu; Jun Ren; Yundai Chen
Journal:  Basic Res Cardiol       Date:  2018-05-09       Impact factor: 17.165

Review 6.  Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond.

Authors:  Baris Bingol; Morgan Sheng
Journal:  Free Radic Biol Med       Date:  2016-04-16       Impact factor: 7.376

Review 7.  Beyond DNA repair: DNA-PK function in cancer.

Authors:  Jonathan F Goodwin; Karen E Knudsen
Journal:  Cancer Discov       Date:  2014-08-28       Impact factor: 39.397

8.  ACG Clinical Guideline: Alcoholic Liver Disease.

Authors:  Ashwani K Singal; Ramon Bataller; Joseph Ahn; Patrick S Kamath; Vijay H Shah
Journal:  Am J Gastroenterol       Date:  2018-01-16       Impact factor: 10.864

9.  DNA-PKcs promotes alcohol-related liver disease by activating Drp1-related mitochondrial fission and repressing FUNDC1-required mitophagy.

Authors:  Hao Zhou; Pingjun Zhu; Jin Wang; Sam Toan; Jun Ren
Journal:  Signal Transduct Target Ther       Date:  2019-12-06
  9 in total

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