Literature DB >> 3219270

The flow cytometry of melanocytic skin lesions.

J A Newton1, R S Camplejohn, D H McGibbon.   

Abstract

DNA flow cytometry was performed on formalin fixed, paraffin embedded melanocytic naevi. DNA aneuploidy was detected in all three types of naevus but was significantly more frequent in those naevi accepted as precursors of malignancy: that is, dysplastic and congenital pigmented hairy naevi. It may be that the presence of DNA aneuploidy has prognostic significance in these naevi. Technical problems were encountered in the analysis of data from melanocytic lesions so that caution is recommended in interpretation of studies using formalin fixed tissue.

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Year:  1988        PMID： 3219270      PMCID： PMC2246814          DOI： 10.1038/bjc.1988.268

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  11 in total

1.  GIANT PIGMENTED NEVI, MELANOMA, AND LEPTOMENINGEAL MELANOCYTOSIS: A CLINICAL AND HISTOPATHOLOGICAL STUDY.

Authors:  W B REED; S W BECKER; S W BECKER; W R NICKEL
Journal:  Arch Dermatol       Date:  1965-02

2.  A flow cytometric study of the significance of DNA aneuploidy in cutaneous lesions.

Authors:  J A Newton; R S Camplejohn; D H McGibbon
Journal:  Br J Dermatol       Date:  1987-08       Impact factor: 9.302

3.  DNA aneuploidy in congenital melanocytic nevi: suggestive evidence for premalignant changes.

Authors:  W Stenzinger; L Suter; J Schumann
Journal:  J Invest Dermatol       Date:  1984-06       Impact factor: 8.551

4.  Congenital nevi. The controversy rages on.

Authors:  J C Alper
Journal:  Arch Dermatol       Date:  1985-06

5.  Cellular DNA content as a marker of neoplasia in man.

Authors:  B Barlogie; B Drewinko; J Schumann; W Göhde; G Dosik; J Latreille; D A Johnston; E J Freireich
Journal:  Am J Med       Date:  1980-08       Impact factor: 4.965

6.  A histologic comparison of congenital and acquired nevomelanocytic nevi.

Authors:  A R Rhodes; R A Silverman; T J Harrist; J W Melski
Journal:  Arch Dermatol       Date:  1985-10

Review 7.  Clinical and biological significance of aneuploidy in human tumours.

Authors:  M L Friedlander; D W Hedley; I W Taylor
Journal:  J Clin Pathol       Date:  1984-09       Impact factor: 3.411

8.  Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry.

Authors:  D W Hedley; M L Friedlander; I W Taylor; C A Rugg; E A Musgrove
Journal:  J Histochem Cytochem       Date:  1983-11       Impact factor: 2.479

9.  Malignant melanoma without metastasis in a giant nevus.

Authors:  A F Borges; A S Lineberger
Journal:  Ann Plast Surg       Date:  1984-05       Impact factor: 1.539

10.  Significance of DNA abnormalities in primary malignant melanoma and nevi, a retrospective flow cytometric study.

Authors:  J H von Roenn; S M Kheir; J M Wolter; J S Coon
Journal:  Cancer Res       Date:  1986-06       Impact factor: 12.701
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  4 in total

Review 1.  Review: assessment of cell proliferation in histological material.

Authors:  P A Hall; D A Levison
Journal:  J Clin Pathol       Date:  1990-03       Impact factor: 3.411

Review 2.  Melanocytic dysplastic naevi occupy the middle ground between benign melanocytic naevi and cutaneous malignant melanomas: emerging clues.

Authors:  M R Hussein
Journal:  J Clin Pathol       Date:  2005-05       Impact factor: 3.411

3.  Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis.

Authors:  Revati Darp; Marc A Vittoria; Neil J Ganem; Craig J Ceol
Journal:  Nat Commun       Date:  2022-07-15       Impact factor: 17.694

Review 4.  Tumour progression and the nature of cancer.

Authors:  W H Clark
Journal:  Br J Cancer       Date:  1991-10       Impact factor: 7.640
  4 in total

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