Literature DB >> 3219232

Effect of erythropoietin on membrane lipid peroxidation, superoxide dismutase, catalase, and glutathione peroxidase of rat RBC.

M Chakraborty1, J Ghosal, T Biswas, A G Datta.   

Abstract

Starved animals having low levels of erythropoietin in blood showed increased MDA, fluorescent pigments, and met-Hb values whereas the hemoglobin concentration decreased significantly on starvation. In vivo and in vitro studies with Ep reversed the effects of starvation and brought these values close to normal. The activities of the enzymes (SOD, catalase, GSH-PX, GR G6PD, and 6PGD) which protect the RBC membrane directly or indirectly from peroxidative threat, decreased on starvation and restored to normal levels after Ep treatment.

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Year:  1988        PMID: 3219232     DOI: 10.1016/0885-4505(88)90099-0

Source DB:  PubMed          Journal:  Biochem Med Metab Biol        ISSN: 0885-4505


  6 in total

Review 1.  Erythropoetin as a novel agent with pleiotropic effects against acute lung injury.

Authors:  Sotirios Kakavas; Theano Demestiha; Panagiotis Vasileiou; Theodoros Xanthos
Journal:  Eur J Clin Pharmacol       Date:  2010-11-11       Impact factor: 2.953

2.  Erythropoietin protects the intestine against ischemia/ reperfusion injury in rats.

Authors:  Ensari Guneli; Zahide Cavdar; Huray Islekel; Sulen Sarioglu; Serhat Erbayraktar; Muge Kiray; Selman Sokmen; Osman Yilmaz; Necati Gokmen
Journal:  Mol Med       Date:  2007 Sep-Oct       Impact factor: 6.354

3.  Red cell lipid peroxidation and antioxidant system in haemodialysed patients: influence of recombinant human erythropoietin (r-HuEPO) treatment.

Authors:  M Boran; C Küçükaksu; M Balk; S Cetin
Journal:  Int Urol Nephrol       Date:  1998       Impact factor: 2.370

4.  Effect of Cu(2+)-ascorbic acid on lipid peroxidation, Mg(2+)-ATPase activity and spectrin of RBC membrane and reversal by erythropoietin.

Authors:  A Chattopadhyay; T D Das Choudhury; M K Basu; A G Datta
Journal:  Mol Cell Biochem       Date:  1992-12-02       Impact factor: 3.396

5.  The antioxidant effect of erythropoietin on thalassemic blood cells.

Authors:  Johnny Amer; Mutaz Dana; Eitan Fibach
Journal:  Anemia       Date:  2010-12-21

Review 6.  The role of erythropoietin as an inhibitor of tissue ischemia.

Authors:  Nikolaos Paschos; Marios G Lykissas; Alexandros E Beris
Journal:  Int J Biol Sci       Date:  2008-06-10       Impact factor: 6.580

  6 in total

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