Literature DB >> 32189004

Increasing Costs of Skin Cancer due to Increasing Incidence and Introduction of Pharmaceuticals, 2007-2017.

Eline Noels1, Loes Hollestein, Kees Luijkx, Marieke Louwman, Carin de Uyl-de Groot, Renate van den Bos, Astrid van der Veldt, Dirk Grünhagen, Marlies Wakkee.   

Abstract

Skin cancer is the most common type of cancer and its incidence is increasing. The objective of this study was to describe the trends in reimbursed drug and hospital costs of benign and (pre)malignant skin tumours, and to present future projections. Therefore, nationwide hospital and drug reimbursement data (for the period 2007-17) were used. In 2017, malignant skin tumours were the 4th most costly cancer in the Netherlands (after breast, colorectal, and lung cancer). The total costs for skin tumours increased from €278 million for 384,390 patients (in 2007) to €465 million for 578,355 patients (in 2017). Drug costs increased from €0.7 million to €121 million (over the period 2007-17), resulting in a 26% share of overall costs in 2017. Future costs are projected to reach €1.35 billion in 2030. In conclusion, the increasing costs of skin cancer are strongly affected by the increasing incidence and introduction of expensive drugs, and future projections are for an alarming increase.

Entities:  

Keywords:  health expenditure; healthcare costs; skin cancer: skin neoplasm

Mesh:

Substances:

Year:  2020        PMID: 32189004      PMCID: PMC9137355          DOI: 10.2340/00015555-3463

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   3.875


  33 in total

1.  Universal mandatory health insurance in the Netherlands: a model for the United States?

Authors:  Wynand P M M van de Ven; Frederik T Schut
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Journal:  Lancet Oncol       Date:  2016-07-30       Impact factor: 41.316

Review 3.  More Than Many: How to Manage the Most Frequent Cancer?

Authors:  Loes Hollestein; Martin Weinstock; Emma Le Roux; Catherine Olsen
Journal:  J Invest Dermatol       Date:  2017-09       Impact factor: 8.551

4.  Trends of cutaneous squamous cell carcinoma in the Netherlands: increased incidence rates, but stable relative survival and mortality 1989-2008.

Authors:  L M Hollestein; E de Vries; T Nijsten
Journal:  Eur J Cancer       Date:  2012-02-16       Impact factor: 9.162

5.  Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006).

Authors:  Jacob Schachter; Antoni Ribas; Georgina V Long; Ana Arance; Jean-Jacques Grob; Laurent Mortier; Adil Daud; Matteo S Carlino; Catriona McNeil; Michal Lotem; James Larkin; Paul Lorigan; Bart Neyns; Christian Blank; Teresa M Petrella; Omid Hamid; Honghong Zhou; Scot Ebbinghaus; Nageatte Ibrahim; Caroline Robert
Journal:  Lancet       Date:  2017-08-16       Impact factor: 79.321

6.  Prevalence of a history of skin cancer in 2007: results of an incidence-based model.

Authors:  Robert S Stern
Journal:  Arch Dermatol       Date:  2010-03

7.  Burden of skin cancer in Belgium and cost-effectiveness of primary prevention by reducing ultraviolet exposure.

Authors:  Lore Pil; Isabelle Hoorens; Katrien Vossaert; Vibeke Kruse; Isabelle Tromme; Niko Speybroeck; Lieve Brochez; Lieven Annemans
Journal:  Prev Med       Date:  2016-10-03       Impact factor: 4.018

Review 8.  Health system costs of skin cancer and cost-effectiveness of skin cancer prevention and screening: a systematic review.

Authors:  Louisa G Gordon; David Rowell
Journal:  Eur J Cancer Prev       Date:  2015-03       Impact factor: 2.497

9.  Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

Authors:  Jedd D Wolchok; Vanna Chiarion-Sileni; Rene Gonzalez; Piotr Rutkowski; Jean-Jacques Grob; C Lance Cowey; Christopher D Lao; John Wagstaff; Dirk Schadendorf; Pier F Ferrucci; Michael Smylie; Reinhard Dummer; Andrew Hill; David Hogg; John Haanen; Matteo S Carlino; Oliver Bechter; Michele Maio; Ivan Marquez-Rodas; Massimo Guidoboni; Grant McArthur; Celeste Lebbé; Paolo A Ascierto; Georgina V Long; Jonathan Cebon; Jeffrey Sosman; Michael A Postow; Margaret K Callahan; Dana Walker; Linda Rollin; Rafia Bhore; F Stephen Hodi; James Larkin
Journal:  N Engl J Med       Date:  2017-09-11       Impact factor: 91.245

10.  Societal cost of skin cancer in Sweden in 2005.

Authors:  Gustav Tinghög; Per Carlsson; Ingrid Synnerstad; Inger Rosdahl
Journal:  Acta Derm Venereol       Date:  2008       Impact factor: 4.437

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  7 in total

1.  Assessment of Cutaneous Squamous Cell Carcinoma (cSCC) In situ Incidence and the Risk of Developing Invasive cSCC in Patients With Prior cSCC In situ vs the General Population in the Netherlands, 1989-2017.

Authors:  Selin Tokez; Marlies Wakkee; Marieke Louwman; Eline Noels; Tamar Nijsten; Loes Hollestein
Journal:  JAMA Dermatol       Date:  2020-09-01       Impact factor: 10.282

2.  Acceptance of Teledermoscopy by General Practitioners and Dermatologists in Denmark.

Authors:  Tine Vestergaard; Merethe K Andersen; Anette Bygum
Journal:  Dermatol Pract Concept       Date:  2021-04-12

3.  Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, Update 2020.

Authors:  R E Neale; P W Barnes; T M Robson; P J Neale; C E Williamson; R G Zepp; S R Wilson; S Madronich; A L Andrady; A M Heikkilä; G H Bernhard; A F Bais; P J Aucamp; A T Banaszak; J F Bornman; L S Bruckman; S N Byrne; B Foereid; D-P Häder; L M Hollestein; W-C Hou; S Hylander; M A K Jansen; A R Klekociuk; J B Liley; J Longstreth; R M Lucas; J Martinez-Abaigar; K McNeill; C M Olsen; K K Pandey; L E Rhodes; S A Robinson; K C Rose; T Schikowski; K R Solomon; B Sulzberger; J E Ukpebor; Q-W Wang; S-Å Wängberg; C C White; S Yazar; A R Young; P J Young; L Zhu; M Zhu
Journal:  Photochem Photobiol Sci       Date:  2021-01-20       Impact factor: 4.328

4.  Views on mobile health apps for skin cancer screening in the general population: an in-depth qualitative exploration of perceived barriers and facilitators.

Authors:  T E Sangers; M Wakkee; E C Kramer-Noels; T Nijsten; M Lugtenberg
Journal:  Br J Dermatol       Date:  2021-07-05       Impact factor: 11.113

5.  Efficacy, cost-minimization, and budget impact of a personalized discharge letter for basal cell carcinoma patients to reduce low-value follow-up care.

Authors:  Sven van Egmond; Ella D van Vliet; Marlies Wakkee; Loes M Hollestein; Xavier G L V Pouwels; Hendrik Koffijberg; Yesim Misirli; Rachel S L A Bakkum; Maarten T Bastiaens; Nicole A Kukutsch; Albert J Oosting; Elsemieke I Plasmeijer; Annik van Rengen; Kees-Peter de Roos; Tamar E C Nijsten; Esther de Vries; Esther W de Bekker-Grob
Journal:  PLoS One       Date:  2022-01-24       Impact factor: 3.240

6.  Validation of a Market-Approved Artificial Intelligence Mobile Health App for Skin Cancer Screening: A Prospective Multicenter Diagnostic Accuracy Study.

Authors:  Tobias Sangers; Suzan Reeder; Sophie van der Vet; Sharan Jhingoer; Antien Mooyaart; Daniel M Siegel; Tamar Nijsten; Marlies Wakkee
Journal:  Dermatology       Date:  2022-02-04       Impact factor: 5.197

7.  Cost-effectiveness of a policy-based intervention to reduce melanoma and other skin cancers associated with indoor tanning.

Authors:  Martin Eden; Rob Hainsworth; Louisa G Gordon; Tracy Epton; Paul Lorigan; Lesley E Rhodes; Richard Marais; Adele C Green; Katherine Payne
Journal:  Br J Dermatol       Date:  2022-05-18       Impact factor: 11.113

  7 in total

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