Literature DB >> 32188760

Cerebral aneurysm treatment trends in National Inpatient Sample 2007-2016: endovascular therapies favored over surgery.

Alice S Wang1, Jessica K Campos2, Geoffrey P Colby3, Alexander L Coon4, Li-Mei Lin5.   

Abstract

BACKGROUND: Flow modulation is the newest endovascular technique for treatment of cerebral aneurysms.
OBJECTIVE: To investigate changes in aneurysm treatment practice patterns in the USA.
METHODS: From the 2007 to 2016, the National Inpatient Sample databases, hospital discharges associated with unruptured aneurysms (UA), and/or ruptured aneurysms (RA) having undergone surgical clipping (SC) and/or endovascular treatments (EVT) were identified using the International Classification of Diseases codes. Patient demographics, hospital characteristics, and clinical outcomes were reviewed. Five year subgroup analyses were performed for treatment differences.
RESULTS: A total of 39 282 hospital discharges were identified with a significant increase in EVT (UA: SC n=7847 vs EVT n=12 797, p<0.001; RA: SC n=8108 vs EVT n=10 530, p<0.001). Hospitals in the South demonstrated the most significant EVT use regardless of aneurysm status (UA: SC n=258.5±53.6 vs EVT n=480.7±155.8, p<0.001; RA: SC n=285.6±54.3 vs EVT n=393.3±102.9, p=0.003). From 2007 to 2011, there was no significant difference in the mean number of cases for the treatment modalities (UA: SC n=847.4±107.7 vs EVT n=1120.4±254.1, p=0.21; RA: SC n=949.4±52.8 vs EVT n=1054.4±219.6, p=0.85). Comparatively, from 2012 to 2016, significantly more UA and RA were treated endovascularly (UA: SC n=722.0±43.4 vs EVT n=1439.0±419.2, p<0.001; RA: SC n=672.2±61.4 vs EVT n=1051.6±330.2, p=0.02).
CONCLUSIONS: As technological innovations continue to advance the neuroendovascular space, the standard of care for treatment of cerebral aneurysms is shifting further towards endovascular therapies over open surgical approaches in the USA. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  aneurysm; coil; flow diverter; stent

Mesh:

Year:  2020        PMID: 32188760     DOI: 10.1136/neurintsurg-2019-015702

Source DB:  PubMed          Journal:  J Neurointerv Surg        ISSN: 1759-8478            Impact factor:   5.836


  4 in total

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3.  Safety and Efficacy of Stent-Assisted Coiling of Unruptured Intracranial Aneurysms Using Low-Profile Stents in Small Parent Arteries.

Authors:  J Kim; H J Han; W Lee; S K Park; J Chung; Y B Kim; K Y Park
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4.  Treatment of experimental aneurysms with a GPX embolic agent prototype: preliminary angiographic and histological results.

Authors:  Frederik Fries; Toshiki Tomori; Walter J Schulz-Schaeffer; Joshua Jones; Umut Yilmaz; Michael Kettner; Andreas Simgen; Wolfgang Reith; Ruben Mühl-Benninghaus
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  4 in total

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