| Literature DB >> 32188661 |
Oluwatosin Kayode1, Paul Underwood2, Ravi Dissanayake2, David Scott-Coombes3, Subramaniam Nagasayi2.
Abstract
We report a case of a 72-year-old woman who presented with ST-elevation myocardial infarction (STEMI). However, coronary angiography showed unobstructed arteries while echocardiography (ECHO) showed severe left ventricular (LV) apical hypokinesia with ejection fraction (EF) of 25-30%. Seven months later she presented with a transient ischaemic attack and a repeat ECHO showed a normal EF.A few months later, she was diagnosed with breast cancer and as part of staging procedure, an incidental left adrenal mass was identified. This was biochemically confirmed as phaeochromocytoma (PY) and she underwent laparoscopic adrenalectomy.PY is a rare catecholamine secreting tumour arising from adrenomedullary chromaffin cells. Excessive catecholamine-induced stimulation can present as transient, reversible cardiomyopathy similar to Takotsubo cardiomyopathy and cerebrovascular events. The diagnosis of PY is often delayed but it is important to recognize PY as a cause of reversible cardiomyopathy. Early intervention is essential to improve mortality from cardiovascular and cerebrovascular complications. © Royal College of Physicians 2020. All rights reserved.Entities:
Keywords: Acute myocardial infarction; Takotsubo cardiomyopathy; phaeochromocytoma; transient ischemic attack
Mesh:
Year: 2020 PMID: 32188661 PMCID: PMC7081805 DOI: 10.7861/clinmed.2019-0494
Source DB: PubMed Journal: Clin Med (Lond) ISSN: 1470-2118 Impact factor: 2.659