Literature DB >> 32188661

Phaeochromocytoma presenting as Takotsubo cardiomyopathy.

Oluwatosin Kayode1, Paul Underwood2, Ravi Dissanayake2, David Scott-Coombes3, Subramaniam Nagasayi2.   

Abstract

We report a case of a 72-year-old woman who presented with ST-elevation myocardial infarction (STEMI). However, coronary angiography showed unobstructed arteries while echocardiography (ECHO) showed severe left ventricular (LV) apical hypokinesia with ejection fraction (EF) of 25-30%. Seven months later she presented with a transient ischaemic attack and a repeat ECHO showed a normal EF.A few months later, she was diagnosed with breast cancer and as part of staging procedure, an incidental left adrenal mass was identified. This was biochemically confirmed as phaeochromocytoma (PY) and she underwent laparoscopic adrenalectomy.PY is a rare catecholamine secreting tumour arising from adrenomedullary chromaffin cells. Excessive catecholamine-induced stimulation can present as transient, reversible cardiomyopathy similar to Takotsubo cardiomyopathy and cerebrovascular events. The diagnosis of PY is often delayed but it is important to recognize PY as a cause of reversible cardiomyopathy. Early intervention is essential to improve mortality from cardiovascular and cerebrovascular complications. © Royal College of Physicians 2020. All rights reserved.

Entities:  

Keywords:  Acute myocardial infarction; Takotsubo cardiomyopathy; phaeochromocytoma; transient ischemic attack

Mesh:

Year:  2020        PMID: 32188661      PMCID: PMC7081805          DOI: 10.7861/clinmed.2019-0494

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  5 in total

1.  Pheochromocytoma-Induced Takotsubo Cardiomyopathy.

Authors:  Majed Afana; Rishi J Panchal; Rebecca M Simon; Amal Hejab; Sharon W Lahiri; Akshay K Khandelwal; Michael P Hudson
Journal:  Tex Heart Inst J       Date:  2019-04-01

Review 2.  Pheochromocytoma as a reversible cause of cardiomyopathy: Analysis and review of the literature.

Authors:  Rong Zhang; Deepashree Gupta; Stewart G Albert
Journal:  Int J Cardiol       Date:  2017-12-15       Impact factor: 4.164

Review 3.  Takotsubo-like cardiomyopathy in pheochromocytoma.

Authors:  Vikram Agarwal; Gunjan Kant; Nidhi Hans; Franz H Messerli
Journal:  Int J Cardiol       Date:  2011-04-07       Impact factor: 4.164

4.  Pheochromocytoma underlying hypertension, stroke, and dilated cardiomyopathy.

Authors:  Pi Chi Lin; Jen Te Hsu; Chang Min Chung; Shih Tai Chang
Journal:  Tex Heart Inst J       Date:  2007

Review 5.  Acute and Chronic Pheochromocytoma-Induced Cardiomyopathies: Different Prognoses?: A Systematic Analytical Review.

Authors:  Marie Batisse-Lignier; Bruno Pereira; Pascal Motreff; Romain Pierrard; Christelle Burnot; Charles Vorilhon; Salwan Maqdasy; Béatrice Roche; Francoise Desbiez; Guillaume Clerfond; Bernard Citron; Jean-René Lusson; Igor Tauveron; Romain Eschalier
Journal:  Medicine (Baltimore)       Date:  2015-12       Impact factor: 1.817

  5 in total

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