Literature DB >> 32173577

Failure of pre-exposure prophylaxis with daily tenofovir/emtricitabine and the scenario of delayed HIV seroconversion.

Shui-Shan Lee1, Peter L Anderson2, Tsz-Ho Kwan3, Grace C Y Lui4, Denise P C Chan3, Ngai-Sze Wong3, Krystal C K Lee3, Teddy T N Lam5.   

Abstract

Failure of pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine may occur despite perfect adherence, although this is uncommon. Failure results in breakthrough HIV infection. Delayed seroconversion associated with antiretroviral use may complicate the picture, causing uncertainties in interpreting adherence patterns for establishing the true cause of PrEP failure.
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Antiretroviral; HIV seroconversion; PrEP failure; Pre-exposure prophylaxis

Mesh：

Substances：

Year:  2020        PMID： 32173577     DOI： 10.1016/j.ijid.2020.03.014

Source DB:  PubMed          Journal:  Int J Infect Dis        ISSN： 1201-9712            Impact factor:   3.623


  2 in total

1.  Navigating Human Immunodeficiency Virus Screening Recommendations for People on Pre-Exposure Prophylaxis and the Need to Update Testing Algorithms.

Authors:  Eric A Meyerowitz; Raffaele M Bernardo; Michelle D Collins-Ogle; Jonathan M Czeresnia; Cariane M Matos; Caroline Mullis; Heather B Root; Julián A Torres-Isasiga; Helen Tsai; Barry S Zingman
Journal:  Open Forum Infect Dis       Date:  2022-04-15       Impact factor: 4.423

2.  Casting a Wide Net: HIV Drug Resistance Monitoring in Pre-Exposure Prophylaxis Seroconverters in the Global Evaluation of Microbicide Sensitivity Project.

Authors:  Lisa Levy; Jill M Peterson; Lauren D Kudrick; Bhavna Chohan; Everline Bosek; Irene Mukui; Mary Mugambi; Sarah Masyuko; Owen Mugurungi; Nonhlanhla Ndlovu; Imelda Mahaka; Megan Dunbar; Anita Hettema; Rudo A P Kuwengwa; Sindy Matse; Saiqa Mullick; Letitia Greener; Cara O'Connor; Diantha Pillay; Maria Fawzy; John W Mellors; Urvi M Parikh
Journal:  Glob Health Sci Pract       Date:  2022-04-29
  2 in total

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