Literature DB >> 32169216

Terminating G-Protein Coupling: Structural Snapshots of GPCR-β-Arrestin Complexes.

Madhu Chaturvedi1, Jagannath Maharana1, Arun K Shukla2.   

Abstract

β-arrestins (βarrs) play multifaceted roles in the signaling and regulation of G-protein-coupled receptors (GPCRs) including their desensitization and endocytosis. Recently determined cryo-EM structures of two different GPCRs in complex with βarr1 provide the first glimpse of GPCR-βarr engagement and a structural framework to understand their interaction.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID： 32169216      PMCID： PMC7115862          DOI： 10.1016/j.cell.2020.02.047

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

1.  Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms.

Authors:  Eshan Ghosh; Hemlata Dwivedi; Mithu Baidya; Ashish Srivastava; Punita Kumari; Tomek Stepniewski; Hee Ryung Kim; Mi-Hye Lee; Jaana van Gastel; Madhu Chaturvedi; Debarati Roy; Shubhi Pandey; Jagannath Maharana; Ramon Guixà-González; Louis M Luttrell; Ka Young Chung; Somnath Dutta; Jana Selent; Arun K Shukla
Journal:  Cell Rep       Date:  2019-09-24       Impact factor: 9.423

Review 2.  Novel Structural Insights into GPCR-β-Arrestin Interaction and Signaling.

Authors:  Ravi Ranjan; Hemlata Dwivedi; Mithu Baidya; Mohit Kumar; Arun K Shukla
Journal:  Trends Cell Biol       Date:  2017-06-23       Impact factor: 20.808

3.  Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.

Authors:  X Edward Zhou; Yuanzheng He; Parker W de Waal; Xiang Gao; Yanyong Kang; Ned Van Eps; Yanting Yin; Kuntal Pal; Devrishi Goswami; Thomas A White; Anton Barty; Naomi R Latorraca; Henry N Chapman; Wayne L Hubbell; Ron O Dror; Raymond C Stevens; Vadim Cherezov; Vsevolod V Gurevich; Patrick R Griffin; Oliver P Ernst; Karsten Melcher; H Eric Xu
Journal:  Cell       Date:  2017-07-27       Impact factor: 41.582

Review 4.  G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

Authors:  Krishna Sriram; Paul A Insel
Journal:  Mol Pharmacol       Date:  2018-01-03       Impact factor: 4.436

5.  A complex structure of arrestin-2 bound to a G protein-coupled receptor.

Authors:  Wanchao Yin; Zhihai Li; Mingliang Jin; Yu-Ling Yin; Parker W de Waal; Kuntal Pal; Yanting Yin; Xiang Gao; Yuanzheng He; Jing Gao; Xiaoxi Wang; Yan Zhang; Hu Zhou; Karsten Melcher; Yi Jiang; Yao Cong; X Edward Zhou; Xuekui Yu; H Eric Xu
Journal:  Cell Res       Date:  2019-11-27       Impact factor: 25.617

6.  Visualization of arrestin recruitment by a G-protein-coupled receptor.

Authors:  Arun K Shukla; Gerwin H Westfield; Kunhong Xiao; Rosana I Reis; Li-Yin Huang; Prachi Tripathi-Shukla; Jiang Qian; Sheng Li; Adi Blanc; Austin N Oleskie; Anne M Dosey; Min Su; Cui-Rong Liang; Ling-Ling Gu; Jin-Ming Shan; Xin Chen; Rachel Hanna; Minjung Choi; Xiao Jie Yao; Bjoern U Klink; Alem W Kahsai; Sachdev S Sidhu; Shohei Koide; Pawel A Penczek; Anthony A Kossiakoff; Virgil L Woods; Brian K Kobilka; Georgios Skiniotis; Robert J Lefkowitz
Journal:  Nature       Date:  2014-06-22       Impact factor: 49.962

7.  C-edge loops of arrestin function as a membrane anchor.

Authors:  Ciara C M Lally; Brian Bauer; Jana Selent; Martha E Sommer
Journal:  Nat Commun       Date:  2017-02-21       Impact factor: 14.919

Review 8.  GPCR Signaling Regulation: The Role of GRKs and Arrestins.

Authors:  Vsevolod V Gurevich; Eugenia V Gurevich
Journal:  Front Pharmacol       Date:  2019-02-19       Impact factor: 5.810

9.  Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc.

Authors:  Dean P Staus; Hongli Hu; Michael J Robertson; Alissa L W Kleinhenz; Laura M Wingler; William D Capel; Naomi R Latorraca; Robert J Lefkowitz; Georgios Skiniotis
Journal:  Nature       Date:  2020-01-16       Impact factor: 49.962

10.  Structure of the neurotensin receptor 1 in complex with β-arrestin 1.

Authors:  Weijiao Huang; Matthieu Masureel; Qianhui Qu; John Janetzko; Asuka Inoue; Hideaki E Kato; Michael J Robertson; Khanh C Nguyen; Jeffrey S Glenn; Georgios Skiniotis; Brian K Kobilka
Journal:  Nature       Date:  2020-01-16       Impact factor: 69.504
  10 in total
  8 in total

1.  Molecular basis for the selective G protein signaling of somatostatin receptors.

Authors:  Sijia Chen; Xiao Teng; Sanduo Zheng
Journal:  Nat Chem Biol       Date:  2022-09-22       Impact factor: 16.174

2.  Key phosphorylation sites in GPCRs orchestrate the contribution of β-Arrestin 1 in ERK1/2 activation.

Authors:  Mithu Baidya; Punita Kumari; Hemlata Dwivedi-Agnihotri; Shubhi Pandey; Madhu Chaturvedi; Tomasz Maciej Stepniewski; Kouki Kawakami; Yubo Cao; Stéphane A Laporte; Jana Selent; Asuka Inoue; Arun K Shukla
Journal:  EMBO Rep       Date:  2020-07-26       Impact factor: 9.071

3.  Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors.

Authors:  Shubhi Pandey; Punita Kumari; Mithu Baidya; Ryoji Kise; Yubo Cao; Hemlata Dwivedi-Agnihotri; Ramanuj Banerjee; Xaria X Li; Cedric S Cui; John D Lee; Kouki Kawakami; Jagannath Maharana; Ashutosh Ranjan; Madhu Chaturvedi; Gagan Deep Jhingan; Stéphane A Laporte; Trent M Woodruff; Asuka Inoue; Arun K Shukla
Journal:  Mol Cell       Date:  2021-09-27       Impact factor: 19.328

4.  miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1.

Authors:  Alessandro Matarese; Jessica Gambardella; Angela Lombardi; Xujun Wang; Gaetano Santulli
Journal:  Cells       Date:  2020-07-06       Impact factor: 6.600

5.  Follicle-Stimulating Hormone Induces Lipid Droplets via Gαi/o and β-Arrestin in an Endometrial Cancer Cell Line.

Authors:  Niamh S Sayers; Priyanka Anujan; Henry N Yu; Stephen S Palmer; Jaya Nautiyal; Stephen Franks; Aylin C Hanyaloglu
Journal:  Front Endocrinol (Lausanne)       Date:  2022-02-03       Impact factor: 5.555

Review 6.  Strategies for Site-Specific Labeling of Receptor Proteins on the Surfaces of Living Cells by Using Genetically Encoded Peptide Tags.

Authors:  Philipp Wolf; Georgina Gavins; Annette G Beck-Sickinger; Oliver Seitz
Journal:  Chembiochem       Date:  2021-02-26       Impact factor: 3.164

7.  Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides.

Authors:  Paula Morales; Marta Bruix; M Angeles Jiménez
Journal:  Int J Mol Sci       Date:  2020-10-30       Impact factor: 5.923

8.  Quantifying the Kinetics of Signaling and Arrestin Recruitment by Nervous System G-Protein Coupled Receptors.

Authors:  Sam R J Hoare; Paul H Tewson; Shivani Sachdev; Mark Connor; Thomas E Hughes; Anne Marie Quinn
Journal:  Front Cell Neurosci       Date:  2022-01-17       Impact factor: 5.505
  8 in total

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