Aim: To explore the prognostic value of the systemic inflammatory marker (SIM) based on neutrophil, lymphocyte and monocyte counts in head and neck squamous cell carcinoma (HNSCC) patients. Patients & methods: We retrospectively collected the data of 367 patients with HNSCC who underwent surgery. The Kaplan-Meier survival analysis and Cox regression analysis were conducted on disease-free survival and overall survival. Results: A high SIM (>1.34) was associated with larger tumor size, advanced clinical stage and shorter survival time. The survival analysis showed that only clinical stage and SIM were independent prognostic indicators of disease-free survival and overall survival. Conclusion: The SIM positively correlated with tumor progression and might be a powerful prognostic indicator of poor outcome in patients with HNSCC.
Aim: To explore the prognostic value of the systemic inflammatory marker (SIM) based on neutrophil, lymphocyte and monocyte counts in head and neck squamous cell carcinoma (HNSCC) patients. Patients & methods: We retrospectively collected the data of 367 patients with HNSCC who underwent surgery. The Kaplan-Meier survival analysis and Cox regression analysis were conducted on disease-free survival and overall survival. Results: A high SIM (>1.34) was associated with larger tumor size, advanced clinical stage and shorter survival time. The survival analysis showed that only clinical stage and SIM were independent prognostic indicators of disease-free survival and overall survival. Conclusion: The SIM positively correlated with tumor progression and might be a powerful prognostic indicator of poor outcome in patients with HNSCC.
Entities:
Keywords:
head and neck squamous cell carcinoma; prognosis; survival; systemic inflammatory marker
Authors: Piergiorgio Gaudioso; Daniele Borsetto; Giancarlo Tirelli; Margherita Tofanelli; Fiordaliso Cragnolini; Anna Menegaldo; Cristoforo Fabbris; Gabriele Molteni; Daniele Marchioni; Piero Nicolai; Paolo Bossi; Andrea Ciorba; Stefano Pelucchi; Chiara Bianchini; Simone Mauramati; Marco Benazzo; Vittorio Giacomarra; Roberto Di Carlo; Mantegh Sethi; Jerry Polesel; Jonathan Fussey; Paolo Boscolo-Rizzo Journal: Support Care Cancer Date: 2021-01-29 Impact factor: 3.359
Authors: Pierluigi Mariani; Diana Russo; Marco Maisto; Giuseppe Troiano; Vito Carlo Alberto Caponio; Marco Annunziata; Luigi Laino Journal: J Oral Pathol Med Date: 2021-12-09 Impact factor: 3.539