Literature DB >> 32166549

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy by laparoscopy via a single-port approach for low-grade peritoneal malignancy.

F Dumont1, E Duchalais2, A Aumont3, E Thibaudeau3.   

Abstract

BACKGROUND: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a long and complex procedure. A minimal invasive approach is rarely performed. The feasibility of laparoscopic CRS and HIPEC via a single port (SP) approach is unknown. The aim of this study was to assess the feasibility of CRS and HIPEC with a SP approach.
METHODS: This study is IDEAL stage I-IIa. Patients with low grade and limited peritoneal malignancy were included in a tertiary care cancer center. Intra- and post-operative adverse events were recorded and classified according to medical and surgical dedicated classifications. The main objective measurement to assess feasibility was the conversion to open or multiport surgery.
RESULTS: A total of 12 highly selected patients were assessed. The median operating time was 240 min (range, 180-360) and two near miss events were reported. Two conversions to open and multiport surgery occurred. The median comprehensive complication index was 0 (range, 0-42.6) with two severe adverse events (Clavien-Dindo or CTC-AE ≥ 3). The median length of stay was 8.5 days (range, 5-13).
CONCLUSION: CRS and HIPEC via a laparoscopic SP approach are feasible and safe in the short term. The next step should be a prospective development study.

Entities:  

Keywords:  Cytoreductive surgery; HIPEC; Laparoscopy; Single port

Mesh:

Year:  2020        PMID: 32166549     DOI: 10.1007/s00464-020-07492-w

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  2 in total

1.  Phase II randomized study on tissue distribution and pharmacokinetics of cisplatin according to different levels of intra-abdominal pressure (IAP) during HIPEC (NCT02949791).

Authors:  Shigeki Kusamura; Norfarizan Azmi; Luca Fumagalli; Dario Baratti; Marcello Guaglio; Adalberto Cavalleri; Giulia Garrone; Luigi Battaglia; Francesco Barretta; Marcello Deraco
Journal:  Eur J Surg Oncol       Date:  2019-06-21       Impact factor: 4.424

2.  Resection of rectal cancer via an abdominal single-port access: short-term results and comparison with standard laparoscopy.

Authors:  Isabelle Sourrouille; Frédéric Dumont; Diane Goéré; Charles Honoré; Dominique Elias
Journal:  Dis Colon Rectum       Date:  2013-11       Impact factor: 4.585

  2 in total
  1 in total

1.  Laparoscopic cytoreductive surgery and HIPEC in LAMN with small volume of peritoneal disease: a valuable option of treatment for good patient-related experience measures (PREMs).

Authors:  Caterina Cusumano; Sébastien Carrere; Alix Bouillin; Stéphanie Nougaret; Lakhdar Khellaf; François Quénet; Olivia Sgarbura
Journal:  Surg Endosc       Date:  2021-11-29       Impact factor: 3.453

  1 in total

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