Literature DB >> 32165465

Melatonin for children with autism spectrum disorder.

Tyler Yan, Ran D Goldman.   

Abstract

Question I have several patients with autism spectrum disorder (ASD) who experience difficulties with sleep, affecting the quality of life of both the child and the family. Is melatonin an effective treatment for sleep problems in children with this condition?Answer Autism spectrum disorder is prevalent among children in Canada and globally, with most affected children experiencing troubles with sleep. Behavioural therapy is the first-line treatment for sleep problems in children with ASD, and melatonin has been reported to be effective and safe in this population as an alternative or adjunctive treatment. A new pediatric, prolonged-release formulation of melatonin is not yet available in Canada, but initial studies in Europe have indicated that it is a potentially effective treatment for sleep problems in children with ASD. Copyright© the College of Family Physicians of Canada.

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Year:  2020        PMID： 32165465      PMCID： PMC8302336     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  22 in total

Review 1.  Melatonin in autism spectrum disorders: a systematic review and meta-analysis.

Authors:  Daniel A Rossignol; Richard E Frye
Journal:  Dev Med Child Neurol       Date:  2011-04-19       Impact factor: 5.449

Review 2.  Assessment and pharmacologic treatment of sleep disturbance in autism.

Authors:  Kyle P Johnson; Beth A Malow
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2008-10

3.  Prolonged-release melatonin for children with neurodevelopmental disorders.

Authors:  Hélène De Leersnyder; Nava Zisapel; Moshe Laudon
Journal:  Pediatr Neurol       Date:  2011-07       Impact factor: 3.372

Review 4.  Role of the melatonin system in the control of sleep: therapeutic implications.

Authors:  Seithikurippu R Pandi-Perumal; Venkatramanujan Srinivasan; D Warren Spence; Daniel P Cardinali
Journal:  CNS Drugs       Date:  2007       Impact factor: 5.749

Review 5.  The epidemiology and global burden of autism spectrum disorders.

Authors:  A J Baxter; T S Brugha; H E Erskine; R W Scheurer; T Vos; J G Scott
Journal:  Psychol Med       Date:  2014-08-11       Impact factor: 7.723

Review 6.  A practice pathway for the identification, evaluation, and management of insomnia in children and adolescents with autism spectrum disorders.

Authors:  Beth A Malow; Kelly Byars; Kyle Johnson; Shelly Weiss; Pilar Bernal; Suzanne E Goldman; Rebecca Panzer; Daniel L Coury; Dan G Glaze
Journal:  Pediatrics       Date:  2012-11       Impact factor: 7.124

Review 7.  Advances in the research of melatonin in autism spectrum disorders: literature review and new perspectives.

Authors:  Sylvie Tordjman; Imen Najjar; Eric Bellissant; George M Anderson; Marianne Barburoth; David Cohen; Nemat Jaafari; Olivier Schischmanoff; Rémi Fagard; Enas Lagdas; Solenn Kermarrec; Sophie Ribardiere; Michel Botbol; Claire Fougerou; Guillaume Bronsard; Julie Vernay-Leconte
Journal:  Int J Mol Sci       Date:  2013-10-14       Impact factor: 5.923

8.  Long-Term Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children with Autism Spectrum Disorder.

Authors:  Athanasios Maras; Carmen M Schroder; Beth A Malow; Robert L Findling; John Breddy; Tali Nir; Shiri Shahmoon; Nava Zisapel; Paul Gringras
Journal:  J Child Adolesc Psychopharmacol       Date:  2018-10-11       Impact factor: 2.576

9.  Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.

Authors:  Carmen M Schroder; Beth A Malow; Athanasios Maras; Raun D Melmed; Robert L Findling; John Breddy; Tali Nir; Shiri Shahmoon; Nava Zisapel; Paul Gringras
Journal:  J Autism Dev Disord       Date:  2019-08

10.  Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial.

Authors:  P Gringras; C Gamble; A P Jones; L Wiggs; P R Williamson; A Sutcliffe; P Montgomery; W P Whitehouse; I Choonara; T Allport; A Edmond; R Appleton
Journal:  BMJ       Date:  2012-11-05
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