Literature DB >> 32164839

An M. tuberculosis Metabolic Enzyme Moonlights as an Anti-Inflammatory Effector Protein.

Tina Truong1, Bennett H Penn2.   

Abstract

The mechanisms by which Mycobacterium tuberculosis evades host immunity remain enigmatic. In a recent study in the journal Nature, Wang et al. report that an enzyme acting in the bacterial cytoplasm to degrade lipids also acts as an effector protein in the host cell cytoplasm to suppress inflammation.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 32164839     DOI: 10.1016/j.chom.2020.02.012

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  2 in total

1.  Mycobacterium tuberculosis RipA Dampens TLR4-Mediated Host Protective Response Using a Multi-Pronged Approach Involving Autophagy, Apoptosis, Metabolic Repurposing, and Immune Modulation.

Authors:  Mohd Shariq; Neha Quadir; Neha Sharma; Jasdeep Singh; Javaid A Sheikh; Mohd Khubaib; Seyed E Hasnain; Nasreen Z Ehtesham
Journal:  Front Immunol       Date:  2021-03-04       Impact factor: 7.561

Review 2.  Host Cell Targets of Released Lipid and Secreted Protein Effectors of Mycobacterium tuberculosis.

Authors:  Jacques Augenstreich; Volker Briken
Journal:  Front Cell Infect Microbiol       Date:  2020-10-23       Impact factor: 5.293

  2 in total

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