Sarah Ann Barbara1, Vicky Kritikos2, David B Price3, Sinthia Bosnic-Anticevich4. 1. Medicine, The University of Sydney, Sydney, Australia. 2. Respiratory Medicines Group, Woolcock Institute of Medical Research, Glebe, Australia. 3. Academic Primary Care, University of Aberdeen, Aberdeen, UK. 4. Quality Use of Respiratory Medicines, Woolcock Institute of Medical Research, Glebe, Australia.
Abstract
OBJECTIVES: Correct inhaler technique is essential to optimal clinical outcomes in asthma patients. The study aim was to use real-life data from the iHARP database to determine patient factors associated with the performance of inhaler technique errors associated with poor asthma outcomes (as identified in the Critikal study) in patients with asthma prescribed the Turbuhaler (TH), Metered Dose Inhaler (MDI), and Accuhaler (AH) device. METHODS: This was a retrospective cross-sectional study using the iHARP database, a multinational initiative including questionnaires and technique review. Identification of inhaler technique errors specifically associated with poor asthma outcomes was performed by reference to the Critikal study. Multivariable logistic regression was used to identify demographic and clinical factors associated with ≥ 1 of these errors. RESULTS: Factors significantly associated with ≥ 1 inhaler technique error and worsening asthma outcomes for the TH cohort include female gender, very poor to average self-assessment of inhaler technique; for the MDI cohort, female gender, secondary education, and current smoking status; and, in the AH cohort, lack of inhaler technique review by a trained healthcare professional in the previous twelve months and very poor to average self-assessment of inhaler technique. CONCLUSIONS: Numerous specific patient demographic and clinical factors associated with the performance of these errors have been identified, differing according to device. Inhaler technique error associated with poor asthma outcomes is further widespread across devices. Knowledge of these factors and the frequency of their occurence may assist in optimizing device selection and training.
OBJECTIVES: Correct inhaler technique is essential to optimal clinical outcomes in asthma patients. The study aim was to use real-life data from the iHARP database to determine patient factors associated with the performance of inhaler technique errors associated with poor asthma outcomes (as identified in the Critikal study) in patients with asthma prescribed the Turbuhaler (TH), Metered Dose Inhaler (MDI), and Accuhaler (AH) device. METHODS: This was a retrospective cross-sectional study using the iHARP database, a multinational initiative including questionnaires and technique review. Identification of inhaler technique errors specifically associated with poor asthma outcomes was performed by reference to the Critikal study. Multivariable logistic regression was used to identify demographic and clinical factors associated with ≥ 1 of these errors. RESULTS: Factors significantly associated with ≥ 1 inhaler technique error and worsening asthma outcomes for the TH cohort include female gender, very poor to average self-assessment of inhaler technique; for the MDI cohort, female gender, secondary education, and current smoking status; and, in the AH cohort, lack of inhaler technique review by a trained healthcare professional in the previous twelve months and very poor to average self-assessment of inhaler technique. CONCLUSIONS: Numerous specific patient demographic and clinical factors associated with the performance of these errors have been identified, differing according to device. Inhaler technique error associated with poor asthma outcomes is further widespread across devices. Knowledge of these factors and the frequency of their occurence may assist in optimizing device selection and training.
Authors: Juan P Wisnivesky; Jacqueline H Becker; Jyoti Ankam; Steven B Markowitz; Molly Doernberg; Brittany Dickens; Paula Busse; Laura Crowley; Alex Federman; Craig Katz; Jeffrey J Weiss; Adam Gonzalez Journal: J Allergy Clin Immunol Pract Date: 2021-09-14
Authors: Catalina Lizano-Barrantes; Olatz Garin; Alexandra L Dima; Eric van Ganse; Marijn de Bruin; Manon Belhassen; Karina Mayoral; Àngels Pont; Montse Ferrer Journal: Int J Environ Res Public Health Date: 2022-02-23 Impact factor: 3.390