Literature DB >> 32160670

Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis.

Harold A Chapman1, Ying Wei1, Genevieve Montas1, Darren Leong1, Jeffrey A Golden1, Binh N Trinh1, Paul J Wolters1, Claude J Le Saux1, Kirk D Jones1, Nancy K Hills1, Elena Foster2, Justin M Oldham2, Angela L Linderholm2, Prerna Kotak3, Martin Decaris3, Scott Turner3, Jin-Woo Song4.   

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Year:  2020        PMID: 32160670      PMCID: PMC7297220          DOI: 10.1056/NEJMc1915189

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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  5 in total

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Journal:  J Clin Invest       Date:  2017-09-05       Impact factor: 14.808

2.  Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study.

Authors:  Toby M Maher; Susanne Stowasser; Yasuhiko Nishioka; Eric S White; Vincent Cottin; Imre Noth; Moisés Selman; Klaus B Rohr; Andreas Michael; Carina Ittrich; Claudia Diefenbach; R Gisli Jenkins
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3.  Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008).

Authors:  Mario E Lacouture; John C Morris; Donald P Lawrence; Antoinette R Tan; Thomas E Olencki; Geoffrey I Shapiro; Bruce J Dezube; Jay A Berzofsky; Frank J Hsu; Joan Guitart
Journal:  Cancer Immunol Immunother       Date:  2015-01-13       Impact factor: 6.968

4.  Prognostic and predictive biomarkers for patients with idiopathic pulmonary fibrosis treated with pirfenidone: post-hoc assessment of the CAPACITY and ASCEND trials.

Authors:  Margaret Neighbors; Christopher R Cabanski; Thirumalai R Ramalingam; X Rebecca Sheng; Gaik W Tew; Chunyan Gu; Guiquan Jia; Kun Peng; Jill M Ray; Brett Ley; Paul J Wolters; Harold R Collard; Joseph R Arron
Journal:  Lancet Respir Med       Date:  2018-06-29       Impact factor: 30.700

Review 5.  Targeting the TGFβ signalling pathway in disease.

Authors:  Rosemary J Akhurst; Akiko Hata
Journal:  Nat Rev Drug Discov       Date:  2012-09-24       Impact factor: 84.694

  5 in total
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1.  MUC4 is overexpressed in idiopathic pulmonary fibrosis and collaborates with transforming growth factor β inducing fibrotic responses.

Authors:  Javier Milara; Beatriz Ballester; M J Safont; Enrique Artigues; Juan Escrivá; Esteban Morcillo; Julio Cortijo
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Review 2.  Potential protective mechanisms of green tea polyphenol EGCG against COVID-19.

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Review 3.  The COVID-19 pandemic: catching up with the cataclysm.

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Review 4.  Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis.

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Review 5.  Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases.

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Review 6.  Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis.

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7.  Evidence of pyroptosis and ferroptosis extensively involved in autoimmune diseases at the single-cell transcriptome level.

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8.  Blocking LOXL2 and TGFβ1 signalling induces collagen I turnover in precision-cut lung slices derived from patients with idiopathic pulmonary fibrosis.

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9.  Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis.

Authors:  Prathibha R Gajjala; Rajesh K Kasam; Divyalakshmi Soundararajan; Debora Sinner; Steven K Huang; Anil G Jegga; Satish K Madala
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  9 in total

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