Literature DB >> 32159599

Clinical studies using stem cells for treatment of retinal diseases: state of the art.

Carina Costa Cotrim1, Rodrigo Jorge1, Maria Carolina de Oliveira2, Fabiano Pieroni3, André M Vieira Messias1, Rubens Camargo Siqueira1,4.   

Abstract

Degenerative retinal diseases such as retinitis pigmentosa, Stargardt's macular dystrophy, and age-related macular degeneration are characterized by irreversible loss of vision due to direct or indirect photoreceptor damage. No effective treatments exist, but stem cell studies have shown promising results. Our aim with this review was to describe the types of stem cells that are under study, their effects, and the main clinical trials involving them.

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Year:  2020        PMID: 32159599     DOI: 10.5935/0004-2749.20200037

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  4 in total

Review 1.  Human-induced pluripotent stem cells-derived retinal pigmented epithelium, a new horizon for cells-based therapies for age-related macular degeneration.

Authors:  Samaneh Dehghan; Reza Mirshahi; Alireza Shoae-Hassani; Masood Naseripour
Journal:  Stem Cell Res Ther       Date:  2022-05-26       Impact factor: 8.079

2.  Targeted next-generation sequencing identifies ABCA4 mutations in Chinese families with childhood-onset and adult-onset Stargardt disease.

Authors:  Ling-Hui Qu; Xin Jin; Chao Zeng; Nian-Gou Zhou; Yan-Hong Liu; Ye Lin
Journal:  Biosci Rep       Date:  2021-06-25       Impact factor: 3.840

3.  Intravitreal Use of a Bone Marrow Mononuclear Fraction (BMMF) Containing CD34+ Cells in Patients with Stargardt Type Macular Dystrophy.

Authors:  Carina Costa Cotrim; André M Vieira Messias; Rodrigo Jorge; Rubens Camargo Siqueira
Journal:  Stem Cells Int       Date:  2020-12-10       Impact factor: 5.443

4.  Induction of Human Umbilical Mesenchymal Stem Cell Differentiation Into Retinal Pigment Epithelial Cells Using a Transwell-Based Co-culture System.

Authors:  Yu-Hsun Chang; V Bharath Kumar; Yao-Tseng Wen; Chih-Yang Huang; Rong-Kung Tsai; Dah-Ching Ding
Journal:  Cell Transplant       Date:  2022 Jan-Dec       Impact factor: 4.064

  4 in total

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