Literature DB >> 32157509

Neural Stem/Progenitor Cells of Human Olfactory Mucosa for the Treatment of Chronic Spinal Cord Injuries.

A D Voronova1, O V Stepanova2, M P Valikhov2, A V Chadin2, A S Semkina2, V P Chekhonin2.   

Abstract

We studied the efficiency of transplantation of neural stem/progenitor cells from human olfactory mucosa in chronic spinal cord injury. Neural stem/progenitor cells were obtained by a protocol modified by us and transplanted to rats with spinal post-traumatic cysts. It was shown that transplantation of neural stem/progenitor cells from human olfactory lining improved motor activity of hind limbs in the recipient rat with spinal post-traumatic cysts (according to BBB scale).

Entities:  

Keywords:  cell therapy; human olfactory mucosa; neural stem/progenitor cells; spinal cord injuries

Mesh：

Year:  2020        PMID： 32157509     DOI： 10.1007/s10517-020-04749-1

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  2 in total

Review 1.  The immune microenvironment and tissue engineering strategies for spinal cord regeneration.

Authors:  Yuan Feng; Yong Peng; Jing Jie; Yumin Yang; Pengxiang Yang
Journal:  Front Cell Neurosci       Date:  2022-08-04       Impact factor: 6.147

Review 2.  The roles and applications of neural stem cells in spinal cord injury repair.

Authors:  Wen Guo; Xindan Zhang; Jiliang Zhai; Jiajia Xue
Journal:  Front Bioeng Biotechnol       Date:  2022-08-29
  2 in total

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