Literature DB >> 32157501

Cell-based approaches towards treating age-related macular degeneration.

Alireza Baradaran-Rafii1,2, Masoumeh Sarvari3, Sepideh Alavi-Moghadam3, Moloud Payab4, Parisa Goodarzi5, Hamid Reza Aghayan3, Bagher Larijani6, Mostafa Rezaei-Tavirani7, Mahmood Biglar6, Babak Arjmand8,9.   

Abstract

Age-related macular degeneration as one of the most common causes of worldwide vision loss needs a proper approach for treatment. Therein, cell therapy and regenerative medicine can hold a great promise to be an effective approach. Accordingly, some preclinical and clinical studies were conducted to search around the therapeutic influence of stem cells in Age-related macular degeneration models and subjects. Hereupon, the purpose of the current review is to discuss the mechanisms of age-related macular degeneration, appropriate animal models along with suitable dosage and route of stem cell administration for its treatment.

Entities:  

Keywords:  Age-related macular degeneration; Animal models; Cell therapy; Clinical trials

Mesh：

Year:  2020        PMID： 32157501     DOI： 10.1007/s10561-020-09826-3

Source DB:  PubMed          Journal:  Cell Tissue Bank        ISSN： 1389-9333            Impact factor:   1.522


  4 in total

Review 1.  Human-induced pluripotent stem cells-derived retinal pigmented epithelium, a new horizon for cells-based therapies for age-related macular degeneration.

Authors:  Samaneh Dehghan; Reza Mirshahi; Alireza Shoae-Hassani; Masood Naseripour
Journal:  Stem Cell Res Ther       Date:  2022-05-26       Impact factor: 8.079

Review 2.  Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19.

Authors:  Peyvand Parhizkar Roudsari; Sepideh Alavi-Moghadam; Moloud Payab; Forough Azam Sayahpour; Hamid Reza Aghayan; Parisa Goodarzi; Fereshteh Mohamadi-Jahani; Bagher Larijani; Babak Arjmand
Journal:  Cell Tissue Bank       Date:  2020-06-25       Impact factor: 1.522

Review 3.  Mesenchymal stem cell as a novel approach to systemic sclerosis; current status and future perspectives.

Authors:  Mina Abedi; Sepideh Alavi-Moghadam; Moloud Payab; Parisa Goodarzi; Fereshteh Mohamadi-Jahani; Forough Azam Sayahpour; Bagher Larijani; Babak Arjmand
Journal:  Cell Regen       Date:  2020-12-01

4.  Subretinal Implantation of Human Primary RPE Cells Cultured on Nanofibrous Membranes in Minipigs.

Authors:  Lyubomyr Lytvynchuk; Annabelle Ebbert; Hana Studenovska; Richárd Nagymihály; Natasha Josifovska; David Rais; Štěpán Popelka; Lucie Tichotová; Yaroslav Nemesh; Jana Čížková; Jana Juhásová; Štefan Juhás; Pavla Jendelová; Janka Franeková; Igor Kozak; Slaven Erceg; Zbynek Straňák; Brigitte Müller; Zdenka Ellederová; Jan Motlík; Knut Stieger; Taras Ardan; Goran Petrovski
Journal:  Biomedicines       Date:  2022-03-14
  4 in total

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