| Literature DB >> 32154802 |
Carlo Federici1, Patrick Detzel2, Francesco Petracca1, Livia Dainelli2, Giovanni Fattore1,3.
Abstract
[This corrects the article DOI: 10.1186/s40795-018-0263-6.].Entities:
Year: 2019 PMID: 32154802 PMCID: PMC7050750 DOI: 10.1186/s40795-019-0269-8
Source DB: PubMed Journal: BMC Nutr ISSN: 2055-0928
Interventions targeting sodium consumption
| Author (year) | Study Characteristics | Study Outcomes | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Model type | Time horizon | Target foods | Type of intervention(s) | Voluntary or mandatory | Reduction in intake | Reduction in blood pressure (BP) | Life years gained and reduction in the incidence of health outcomes | Results on QOL measures | |
| Cogswell et al. (2017) [29] | Mathematical/Statistical | Not modelled | All processed food | ↓28% in Na content (Health Canada Benchmarks) | Mandatory | 0.61 Na g/day (22%, UI = 0.59–0.63) | – | – | – |
| Choi et al. (2016) [30] | Micro-simulation | 10y | All processed foods | Product reformulated to meet product-specific NSRI criteria extended to all food producers in the US | Mandatory | 0.365 (SE = 0.9) Na g/day (10.9%) | – | Hypertension: 0.97% | – |
| All AMI: 2.59% | |||||||||
| All strokes: 2.67% | |||||||||
| Fatal AMI: 0.36% | |||||||||
| Fatal Strokes: 0.23% | |||||||||
| Food and Drink Industry Ireland (2016) [26] | Mathematical/Statistical | Not modelled | 10 Food macrocategories | Reformulation based on actual FDII voluntary programme | Mandatory extension of existing programme | 0.57 Na g/day (17.8%) in adults | – | – | – |
| Voluntary | 0.06 Na g/day (2.3%) in adults | – | – | – | |||||
| Leroy et al. (2016) [32] | Epidemiological | 1y | F&V, bread, meat, fish, sandwiches, sauces | Strong reformulation based on the Choices Programme criteria | Mandatory | 12.7% daily Na intake | – | Fatal CVD/Strokes deaths averted: 422 | – |
| Cance deaths averted: 187 | |||||||||
| Mild reformulation based on the Choices Programme criteria | Mandatory | 9.3% daily Na intake | – | CVD/Strokes and Cancer deaths averted: 2408 (3.7%) - due to total reductions in Na, SFA and sugar consumption combined | – | ||||
| Masset et al. (2016) [25] | Mathematical/Statistical | Not modelled | Pizza | Reformulation to meet Nestlè Nutrient Profiling targets | Mandatory | 0.14 Na g/day (4%) | – | – | – |
| Nghiem et al. (2016) [42] | Markov | Cohort life-time | All processed foods | 59% substitution of NaCl with other salts (K, Mg) | Mandatory | 1.82 Na g/day (51.5%) | – | – | 12,783 QALYs gained/100000 pop. (UI = 10,348–15,609) |
| 25% substitution of NaCl with other salts (K, Mg) | Mandatory | 0.77 Na g/day (21.8%) | – | – | 5261 QALYs gained/100000 pop. (UI = 4230–6391) | ||||
| Bread | ↓38,5% in NaCl content | Mandatory | 0.28 Na g/day (7.9%) | – | – | 1891 QALYs gained/100000 pop. (UI = 1509–2296) | |||
| ↓11,1% in NaCl content | Mandatory | 0.08 Na g/day (2.3%) | – | – | 678 QALYs gained/100000 pop. (UI = 548–822) | ||||
| Wilson et al. (2016) [43] | Markov | Cohort life-time | All processed foods (bread, processed meats, sauces, snack food, bakery, cheese) | ↓36% in NaCl content across product types | Mandatory | 0.628 Na g/day | – | – | 5304 QALYs gained/100000 pop. (UI = 4270–6478) |
| Voluntary | Same efficacy with higher uncertainty | – | – | 5000 QALYs gained/100000 pop. (UI = 3709–6391) | |||||
| Bread | ↓12–37% in NaCl content across bread types | Mandatory | 0.043 Na g/day | – | – | 387 QALYs gained/100000 pop. (UI = 309–470) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 365 QALYs gained/100000 pop. (UI = 270–461) | |||||
| Processed meats | ↓35–55% in NaCl content overall | Mandatory | 0.069 Na g/day | – | – | 583 QALYs gained/100000 pop. (UI = 470–704) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 552 QALYs gained/100000 pop. (UI = 417–696) | |||||
| Sauces | ↓30–63% in NaCl content across sauces types | Mandatory | 0.104 Na g/day | – | – | 870 QALYs gained/100000 pop. (UI = 700–1057) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 822 QALYs gained/100000 pop. (UI = 626–1039) | |||||
| Combination of bread, processed meats and sauces | – | Mandatory | 0.217 Na g/day | – | – | 1843 QALYs gained/100000 pop. (UI = 1487–2239) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 1743 QALYs gained/100000 pop. (UI = 1326–2204) | |||||
| Snack food | ↓34–48% in NaCl content across snacks types | Mandatory | 0.032 Na g/day | – | – | 265 QALYs gained/100000 pop. (UI = 217–322) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 252 QALYs gained/100000 pop. (UI = 191–317) | |||||
| Bread and bakery products | ↓12–37% in NaCl content across bread types; ↓54–63% in NaCl content across other bakery products | Mandatory | 0.107 Na g/day | – | – | 887 QALYs gained/100000 pop. (UI = 722–1078) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 843 QALYs gained/100000 pop. (UI = 639–1061) | |||||
| Cheese | ↓27–42% in NaCl content across cheese types | Mandatory | 0.045 Na g/day | – | – | 383 QALYs gained/100000 pop. (UI = 309–461) | |||
| Voluntary | Same efficacy with higher uncertainty | – | – | 361 QALYs gained/100000 pop. (UI = 274–457) | |||||
| Bruins et al. (2015) [45] | Mathematical/Statistical | Cohort life-time | Soups | ↓25% in Na content | Mandatory | 0.05 Na g/day | 0.11 mmHg | Strokes: 0.49% | 6.45 DALYs averted/100000 pop |
| AMI: 0.34% | |||||||||
| Angina: 0.34% | |||||||||
| CHF: 0.24% | |||||||||
| Dötsch-Klerk et al. (2015) [23] | Mathematical/Statistical | Not modelled | All processed foods | Products reformulated to meet the 6 g/day NaCl consumption target | Mandatory | US: 1.8 Na g/day (23%) | – | – | – |
| UK: 1.8 Na g/day (27%) | – | – | – | ||||||
| NL: 1.3 Na g/day (19%) | – | – | – | ||||||
| Products reformulated to meet the 5 g/day NaCl consumption target | Mandatory | US: 2.2 Na g/day (28%) | – | – | – | ||||
| UK: 2.1 Na g/day (32%) | – | – | – | ||||||
| NL: 1.8 Na g/day (26%) | – | – | – | ||||||
| Gillespie et al. (2015) [31] | Epidemiological | 10y | All processed foods | ↓30% in NaCl | Mandatory | 0.58 Na g/day (UI = 0.56–0.60) | 0.81 mmHg '(UI = 0.53–1.10) | CHD deaths averted or postponed: 4467 (UI = 2854–6147) | – |
| ↓10% in NaCl | Mandatory | 0.19 Na g/day (UI = 0.18–0.20) | 0.27 mmHg (UI = 0.18–0.37) | CHD deaths averted or postponed: 1502 (UI = 953–2068) | – | ||||
| ↓24% in NaCl | Voluntary (applied to 39% of products) | 0.19 Na g/day (UI = 0.03–0.63) | 0.27 mmHg (UI = 0.04–0.92) | CHD deaths averted or postponed: 1474 (UI = 220–4995) | – | ||||
| Hendriksen et al. (2015) [22] | Mathematical/Statistical | Not modelled | Selected foods contributing to high intakes of NaCl | ↓50% in NaCl content on average | Mandatory | 0.9 Na g/day (37%) | – | – | – |
| Nghiem et al. (2015) [46] | Markov | Cohort life-time | All processed foods | ↓25% in NaCl | Mandatory | 0.525 Na g/day (15%) | – | – | 4783 QALYs gained/100000 pop (UI = 3804–7174) |
| Breads, processed meats and sauces | ↓25% in NaCl | Mandatory | 0.296 Na g/day (9%) | – | – | 2683 QALYs gained/100000 pop (UI = 2161–3256) | |||
| Wilcox et al. (2015) [34] | Epidemiological | 10y | Not modelled | Not modelled | Mandatory | 0.005 Na g/day (10%) (UI = 0.003–0.021) | 1.15 mmHg (UI = 0.57–4.58) | CHD Deaths averted: 497 (UI = 130–3032) | – |
| LYG: 11192 (UI = 5679–41,039) | – | ||||||||
| Collins et al. (2014) [36] | Epidemiological | 10y | Not modelled | ↓15% in NaCl content overall | Voluntary | 1.21 Na g/day (UI = 0.32–1.94) | – | LYG: 14593(UI = 9000–21,049) | – |
| ↓20% in NaCl content overall | Mandatory | 1.62 Na g/day (UI = 0.65–3.11) | – | LYG: 19365(UI = 11,967–27,887) | – | ||||
| Hendriksen et al. (2014) [47] | Markov | 20y (clinical outcomes); cohort life-time (DALYs) | All processed foods | ↓50% in NaCl content on average | Mandatory | 2.3 Na g/day (28%) | 1.5 mmHg (1.2%) | 4.4% AMI (UI = 3.1–5.6%) | 0.5% DALYs averted in the population (UI = 0.37–0.68%) |
| CHF: 1.8% (UI = 1.3–2.3%) | |||||||||
| Strokes: 6% (UI = 4.1–7.8%) | |||||||||
| Increase in life expectancy: 0.7% (UI = 0.5–0.9%) | |||||||||
| Mason et al. (2014) [53] | Epidemiological | 10y | Not modelled | Not modelled | Mandatory | 10% daily Na intake (UI = 5–40%) | – | Tunisia: LYG 2272 (UI = 1151–3361) | – |
| Syria: LYG 11192 (UI = 5679–41,039) | |||||||||
| Palestine: LYG 945 (UI = 479–3479) | |||||||||
| Turkey: LYG 135221 (UI = 68,816–487,712) | |||||||||
| Konfino et al. (2013) [37] | Markov | 10y | All processed foods | ↓8% in NaCl intake (stepped reduction by 4% for the first 2y) | Mandatory (80% of sodium from processed foods) | 0.353 Na g/day | 1.00–2.00 mmHg | Total Deaths: 0.61% | – |
| Fatal CHD: 0.98% | |||||||||
| AMI: 1.48% | |||||||||
| Strokes: 0.99% | |||||||||
| ↓40% in NaCl intake (4% per year for 10y) | Mandatory (80% of sodium from processed foods) | 1.763 Na g/day | 5.00–9.00 mmHg | Total Deaths: 1.77% | – | ||||
| Fatal CHD: 2.63% | |||||||||
| AMI: 4.27% | |||||||||
| Strokes: 2.79% | |||||||||
| Bertram et al. (2012) [38] | Epidemiological | 1y | Bread, margarine, gravy, soups | ↓54% in NaCl content on average | Mandatory | 0.85 Na g/day | – | Strokes: 8% | – |
| CHD: 6.5% | |||||||||
| Hypertensive heart disease: 11% | |||||||||
| Cobiac et al. (2012) [48] | Markov | Cohort life-time | Bread, margarine, breakfast cereals | Based on Heart Foundation Tick Programme: ↓26% in NaCl content in bread; 11% in margarine and 61% in breakfast cereals | Mandatory | 0.009 Na g/day | – | – | 1451 DALYs averted/100000 pop (UI = 1088–1813) |
| Combris et al. (2011) [8] | Mathematical/Statistical | Not modelled | Breakfast cereals | Mild to strong reformulation based on food nutrient distribution | Mandatory | 0.001–0.013 Na g/day (1.4–13.5%) | – | – | – |
| Biscuits/ pastries | 0.0003–0.002 Na g/day (1.70–10.81%) | – | – | – | |||||
| Bread-based products | 0.0023–0.013 Na g/day (1.60–8.8%) | – | – | – | |||||
| Cobiac et al. (2010) [49] | Epidemiological | Cohort life-time | Bread, margarine, breakfast cereals | Based on Heart Foundation Tick Programme: ↓26% in NaCl content in bread; 11% in margarine and 61% in breakfast cereals | Voluntary | 0.009 Na g/day | – | – | 5300 DALYs averted (UI = 2600–9200) |
| Mandatory extension of actual program to all products | – | – | – | 110,000 DALYs averted (UI = 53,000–180,000) | |||||
| Smith-Spangler et al. (2010) [50] | Markov | Cohort life-time | Not modelled | Not modelled | Voluntary | 9.5% daily Na intake (UI = 5–40%) | 1.25 mmHg | Strokes averted: 513885 | 2,060,790 DALYs averted |
| AMI averted: 480538 | |||||||||
| Roodenburg et al. (2009) [27] | Mathematical/Statistical | Not modelled | All processed foods | Reformulation set to meet Choices Programme criteria | Mandatory | 23% daily Na intake (10% adjusting for energy compensation) | – | – | – |
| Rubinstein et al. (2009) [51] | Markov | Cohort life-time | Bread | ↓ to 1 g of NaCl per 100 g of bread | Voluntary | – | 1.33 mmHg | – | 18.7 DALYs averted/100000 pop |
| Murray et al. (2003) [52] | Markov | Cohort life-time | Not modelled | Not modelled | Mandatory | Assumed 30% Na Intake | AmrB: 3.11% on average | – | 600,000 DALYs averted |
| EurA: 3.49% on average | – | 1,300,000 DALYs averted | |||||||
| SearD: 3.49% on average | – | 1,000,000 DALYs averted | |||||||
| Voluntary | Assumed 15% Na Intake | AmrB: 1.56% on average | – | 300,000 DALYs averted in the population | |||||
| EurA: 1.74% on average | – | 700,000 DALYs averted in the population | |||||||
| SearD: 1.75% on average | – | 500,000 DALYs averted in the population | |||||||
Abbreviations: AMI Acute Myocardial Infarction, AmrB Region of the Americas group B, CHD Coronary Heart Disease, CHF Coronary Heart Failure, CVD Cardiovascular diseases, DALY Disability Adjusted Life Years, EurA European Region group A, FDII Food and Drink Industry Ireland, F&V fruit and vegetables, K potassium, LYG Life Years Gained, Mg magnesium, Na sodium, NaCl Sodium Chloride, NL Netherlands, NSRI National Salt Reduction Initiative, QALY Quality Adjusted Life Year, SearD Southeast Asian Region group D, UI Uncertainty Interval, UK United Kingdom, US United States of America