Literature DB >> 32152463

Overcoming microenvironment-mediated protection from ATRA using CYP26-resistant retinoids.

Daniela Hernandez1, Laura Palau1, Kelly Norsworthy1, Nicole M Anders1, Salvador Alonso1, Meng Su1, Martin Petkovich2, Rosh Chandraratna3, Michelle A Rudek1, B Douglas Smith1, Richard J Jones1, Gabriel Ghiaur4.   

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Year:  2020        PMID： 32152463      PMCID： PMC7483812          DOI： 10.1038/s41375-020-0790-4

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  2 in total

1.  Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist.

Authors:  Michael R McKeown; M Ryan Corces; Matthew L Eaton; Chris Fiore; Emily Lee; Jeremy T Lopez; Mei Wei Chen; Darren Smith; Steven M Chan; Julie L Koenig; Kathryn Austgen; Matthew G Guenther; David A Orlando; Jakob Lovén; Christian C Fritz; Ravindra Majeti
Journal:  Cancer Discov       Date:  2017-07-20       Impact factor: 39.397

2.  Selective high affinity retinoic acid receptor alpha or beta-gamma ligands.

Authors:  C Delescluse; M T Cavey; B Martin; B A Bernard; U Reichert; J Maignan; M Darmon; B Shroot
Journal:  Mol Pharmacol       Date:  1991-10       Impact factor: 4.436
  2 in total
  8 in total

1.  CD38 deletion of human primary NK cells eliminates daratumumab-induced fratricide and boosts their effector activity.

Authors:  Meisam Naeimi Kararoudi; Yuya Nagai; Ezgi Elmas; Marcelo de Souza Fernandes Pereira; Syed Abbas Ali; Philip Hollingsworth Imus; Darren Wethington; Ivan Marques Borrello; Dean Anthony Lee; Gabriel Ghiaur
Journal:  Blood       Date:  2020-11-19       Impact factor: 22.113

2.  Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.

Authors:  Katharina Schönberger; Nadine Obier; Mari Carmen Romero-Mulero; Pierre Cauchy; Julian Mess; Polina V Pavlovich; Yu Wei Zhang; Michael Mitterer; Jasmin Rettkowski; Maria-Eleni Lalioti; Karin Jäcklein; Jonathan D Curtis; Betty Féret; Pia Sommerkamp; Claudia Morganti; Keisuke Ito; Norbert B Ghyselinck; Eirini Trompouki; Joerg M Buescher; Erika L Pearce; Nina Cabezas-Wallscheid
Journal:  Cell Stem Cell       Date:  2021-10-26       Impact factor: 25.269

3.  Proteomic Studies of Primary Acute Myeloid Leukemia Cells Derived from Patients Before and during Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid and Valproic Acid.

Authors:  Maria Hernandez-Valladares; Rebecca Wangen; Elise Aasebø; Håkon Reikvam; Frode S Berven; Frode Selheim; Øystein Bruserud
Journal:  Cancers (Basel)       Date:  2021-04-29       Impact factor: 6.639

Review 4.  All-trans retinoic acid in non-promyelocytic acute myeloid leukemia: driver lesion dependent effects on leukemic stem cells.

Authors:  Chi H Nguyen; Alexander M Grandits; Louise E Purton; Heinz Sill; Rotraud Wieser
Journal:  Cell Cycle       Date:  2020-09-08       Impact factor: 4.534

5.  Taking the STING out of acute myeloid leukemia through macrophage-mediated phagocytosis.

Authors:  William Brian Dalton; Gabriel Ghiaur; Linda Ms Resar
Journal:  J Clin Invest       Date:  2022-03-01       Impact factor: 19.456

6.  Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells.

Authors:  Chi Huu Nguyen; Alexander M Grandits; George S Vassiliou; Philipp B Staber; Gerwin Heller; Rotraud Wieser
Journal:  Biomedicines       Date:  2020-09-28

7.  A Phase 1 Study of IRX195183, a RARα-Selective CYP26 Resistant Retinoid, in Patients With Relapsed or Refractory AML.

Authors:  Alexander J Ambinder; Kelly Norsworthy; Daniela Hernandez; Laura Palau; Bogdan Paun; Amy Duffield; Rosh Chandraratna; Martin Sanders; Ravi Varadhan; Richard J Jones; B Douglas Smith; Gabriel Ghiaur
Journal:  Front Oncol       Date:  2020-10-23       Impact factor: 6.244

8.  Endogenous and combination retinoids are active in myelomonocytic leukemias.

Authors:  Orsola Di Martino; Haixia Niu; Gayla Hadwiger; Heikki Kuusanmaki; Margaret A Ferris; Anh Vu; Jeremy Beales; Carl Wagner; María P Menéndez-Gutiérrez; Mercedes Ricote; Caroline Heckman; John S Welch
Journal:  Haematologica       Date:  2021-04-01       Impact factor: 9.941
  8 in total

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