Literature DB >> 32150040

Dallas UtErus Transplant Study: Early Outcomes and Complications of Robot-assisted Hysterectomy for Living Uterus Donors.

Liza Johannesson1, E Colin Koon2, Johanna Bayer1, Gregory J McKenna1, Anji Wall1, Hoylan Fernandez1, Eric J Martinez1, Amar Gupta1, Richard Ruiz1, Nicholas Onaca1, Giuliano Testa1.   

Abstract

BACKGROUND: Uterus transplantation is a treatment for absolute uterine infertility and can be performed with living and deceased donors. Given the safety and increased utilization of robotic assistance with other gynecologic and transplant donor operations, we adopted a robot-assisted approach to donor hysterectomy. This study compared early outcomes and morbidity of the robot-assisted approach to donor hysterectomy with the traditionally performed open approach and addressed whether the robot-assisted approach is safe and offers advantages for the donor.
METHODS: Our institution has performed 18 living donor hysterectomies for uterus transplantation. This retrospective review compared the last 5 cases utilizing a robot-assisted technique and vaginal extraction of the uterus graft with the first 13 cases performed with an open laparotomy technique. Demographic, intraoperative, and postoperative data were examined.
RESULTS: There were no differences between the robot-assisted and the open living donor group with respect to age, body mass index, or gynecological history. Although the median operative time was shorter for the open approach (6.27 versus 10.46 h), the donors' median estimated blood loss, length of hospital stay, and length of sick leave were less with the robot-assisted approach. There was no conversion to open hysterectomy in the robot-assisted cases, and the incidence of complications was similar between the 2 groups. There was no difference in early graft function.
CONCLUSIONS: These preliminary results show that robot-assisted living donor hysterectomy is feasible and safe for the donors; it allows a faster postoperative recovery and the same early graft function.
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2021        PMID: 32150040     DOI: 10.1097/TP.0000000000003211

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  5 in total

Review 1.  Uterus transplantation: state of the art in 2021.

Authors:  Elliott G Richards; Ruth M Farrell; Stephanie Ricci; Uma Perni; Cristiano Quintini; Andreas Tzakis; Tommaso Falcone
Journal:  J Assist Reprod Genet       Date:  2021-05-31       Impact factor: 3.357

Review 2.  Operative and Clinical Outcomes of Minimally Invasive Living-Donor Surgery on Uterus Transplantation: A Literature Review.

Authors:  Yusuke Matoba; Iori Kisu; Kouji Banno; Daisuke Aoki
Journal:  J Clin Med       Date:  2021-01-18       Impact factor: 4.241

3.  Analysis of blood parameters and molecular endometrial markers during early reperfusion in two ovine models of uterus transplantation.

Authors:  Marie Carbonnel; Nathalie Cornet; Aurélie Revaux; Angéline Favre-Inhofer; Laurent Galio; Mariam Raliou; Anne Couturier-Tarrade; Corinne Giraud-Delville; Gilles Charpigny; Valérie Gelin; Olivier Dubois; Barbara Hersant; Romain Bosc; Raphael Coscas; François Vialard; Pascale Chavatte-Palmer; Christophe Richard; Olivier Sandra; Jean-Marc Ayoubi
Journal:  PLoS One       Date:  2021-05-18       Impact factor: 3.240

Review 4.  Robotic live donor hysterectomy.

Authors:  Pernilla Dahm-Kähler; Niclas Kvarnström; Mats Brännström
Journal:  Curr Opin Organ Transplant       Date:  2021-12-01       Impact factor: 2.640

Review 5.  Uterus Transplantation: Revisiting the Question of Deceased Donors versus Living Donors for Organ Procurement.

Authors:  Emily H Frisch; Tommaso Falcone; Rebecca L Flyckt; Andreas G Tzakis; Eric Kodish; Elliott G Richards
Journal:  J Clin Med       Date:  2022-08-03       Impact factor: 4.964

  5 in total

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